Thyroid Surgery for Benign Disease Clinical Trial
Official title:
Does a Single Dose of Steroid Before Thyroidectomy Improve Postoperative Nausea, Pain and Vocal Function?
| Verified date | June 2008 |
| Source | University of Bern |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | Switzerland: Federal Office of Public Health |
| Study type | Interventional |
We evaluated the effects of giving a single dose of steroid before thyroid surgery in a single institutional, double-blinded, randomized controlled trial. Postoperative nausea, pain, and vocal function were significantly improved after steroid administration compared to controls.
| Status | Completed |
| Enrollment | 72 |
| Est. completion date | June 2007 |
| Est. primary completion date | |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Patients undergoing thyroid surgery for benign disease Exclusion Criteria: - Depression - Chronic pain disorder - Insulin dependent diabetes mellitus - History of PONV - Pregnancy - Age < 18 years - Received antiemetic therapy within 48 hours |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator)
| Country | Name | City | State |
|---|---|---|---|
| Switzerland | Department of visceral- and transplant surgery | Bern |
| Lead Sponsor | Collaborator |
|---|---|
| University of Bern |
Switzerland,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Nausea | 0-72 hours postoperative | No | |
| Secondary | Pain, vocal function | 0-72 hours postoperative | No |