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NCT00404469 Clinical Trial

Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

Patellar Tendinopathy / Jumpers Knee Clinical Trial

Official title:
Effects of Peritendinous Corticosteroid Injections, Eccentric Training and Heavy Slow Resistance Training in Patellar Tendinopathy

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00404469
Other study ID # Patellar tendinopathy
Secondary ID
Status Completed
Phase N/A
First received November 27, 2006
Last updated May 21, 2008
Start date March 2006
Est. completion date November 2007

Study information
Verified date May 2008
Source Bispebjerg Hospital
Contact n/a
Is FDA regulated No
Health authority Denmark: Ethics Committee
Study type Interventional

Clinical Trial Summary

We will investigate the effect of peritendinous corticosteroid injections, eccentric training and heavy resistance training in male patellar tendinopathy patients. The purpose is to compare the clinical effect of these three treatments in a randomised controlled trial. Also we wish to investigate the treatment mechanisms responsible for the effectiveness of the three treatments.

Description:

3 interventions groups as described above (n=13 in each group) 12 weeks intervention period. Clinical assessments before and after intervention: VAS, VISA, Tendon thickness, Doppler us activity.

Before and after intervention tendon biopsies will be taken and analyzed for crosslinks and fibril diameter. Also tendon mechanical properties will be measured. Tendon and muscle structural properties will be measured with MRI.

Treatment satisfaction will be stated after intervention period.

Recruitment information / eligibility
Status Completed
Enrollment 39
Est. completion date November 2007
Est. primary completion date
Accepts healthy volunteers No
Gender Male
Age group 18 Years to 55 Years
Eligibility Inclusion Criteria:

- Clinical patellar tendinopathy pain.

- Tendon swelling

- Hypoechoic

- Doppler activity in tendon

Exclusion Criteria:

- Previous knee surgery

- diabetes

- arthritis

- previous steroid injections

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Intervention

Procedure:
• peritendinous corticosteroid injections
1 ml of40mg/ml methylprednisolone acetate at 0 and 4 weeks. 2 week observational
• eccentric decline squat training
eccentric decline unilateral squats performed twice daily. for 12 weeks
• heavy slow resistance training
Heavy slow resistance training for knee extensors. 3/week. total of 12 weeks

Locations
Country Name City State
Denmark Institute of Sports Medicine Copenhagen. Dept 8 1st floor. Bispebjerg Hospital Copenhagen

Sponsors (1)
Lead Sponsor Collaborator
Bispebjerg Hospital

Country where clinical trial is conducted

Denmark,