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A Study Testing the Effect and Safety of Casopitant (GW679769) While Taking Warfarin in Healthy Human Volunteers

Nausea and Vomiting, Chemotherapy-Induced Clinical Trial

Official title:
An Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Steady-State Warfarin When Co-administered With Repeat Doses of Casopitant [GW679769] in Healthy Adult Subjects.

Clinical Trial Summary

GW679769 may affect liver enzymes that metabolize warfarin. This study is designed to test the extent of the GW679769 affect on Warfarin levels in humans.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Nausea and Vomiting, Chemotherapy-Induced
  • Vomiting
Clinical Trial Details
NCT number NCT00404274
Study type Interventional
Source GlaxoSmithKline
Contact
Status Completed
Phase Phase 1
Start date November 1, 2006
Completion date March 18, 2007
View Details
See also
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Completed NCT00104403 - Study Of Prevention of Chemo-Induced Nausea and Vomiting Caused By Moderately Emetogenic Chemotherapy Phase 2
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Completed NCT00460707 - A Study to Assess the Safety and Interaction Between Casopitant and Ketoconazole When Taken By Healthy Adults Phase 1