Rhegmatogenous Retinal Detachment Clinical Trial
Official title:
Assessment of Recovery of Macula Function After Successful Scleral Buckling Surgery for Rhegmatogenous Retinal Detachment
Assess recovery of macula function after successful scleral buckling surgery for rhegmatogenous retinal detachment by using the multifocal ERG in the postoperative period i.e. recovery of functional integrity 2. Assess the relationship between the neurosensory retina and the retinal pigment epithelium/choriocapillaris after scleral buckling i.e. recovery of structural integrity 3. Assess if there is a difference between macula function postoperatively, in eyes with retinal detachments involving the macula and those that do not.
Patients with acute rhegmatogenous retinal detachments managed by scleral buckling surgery
will be recruited into 3 groups. (Please see attached appendix A)
We define the area of the macula as the area within the temporal vascular arcades with the
horizontal radius defined between the optic disc and the foveal centre.
Group A: Macula not detached Group B: Macula partially detached i.e. detachment stops within
the macula Group C: Macula is totally detached
After scleral buckling surgery for the retinal detachment, the patients will be examined at
Day 1, week 1, month1, 3 and 6. During these visits, they will be examined clinically, as
well as undergo tests - refraction, colour vision (D-15) & contrast sensitivity testing, OCT
and multifocal ERG. (Please see attaced visit schedule).
;
Observational Model: Defined Population, Time Perspective: Longitudinal
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04403750 -
Combined Laser-surgical Technology of RRD Treatment
|
N/A | |
Not yet recruiting |
NCT04520789 -
Early Prevention Strategies of Severe Proliferative Vitreoretinopathy Base on Precision Diagnosis of Single Cell Sequencingvitreoretinopathy
|
N/A | |
Recruiting |
NCT04571788 -
Treating Rhegmatogenous Retinal Detachment by Foldable Capsular Buckle
|
||
Completed |
NCT02834559 -
Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachment.
|
Phase 3 | |
Recruiting |
NCT01845571 -
Retinal Detachment - Demographic and Clinical Survey
|
||
Completed |
NCT04891991 -
Intravitreal Infliximab for Proliferative Vitreoretinopathy
|
Phase 2 | |
Recruiting |
NCT02871531 -
Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment in Patients With Extended Criteria
|
N/A | |
Completed |
NCT00757536 -
Primary Vitrectomy With Endolaser or Encircling Band for Rhegmatogenous Retinal Detachment
|
N/A | |
Active, not recruiting |
NCT00370201 -
Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment
|
Phase 3 | |
Recruiting |
NCT05331664 -
Dropless Pars Plana Vitrectomy Study
|
Phase 4 | |
Completed |
NCT02841306 -
Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment
|
Phase 1 | |
Not yet recruiting |
NCT02185469 -
Corneal Endothelial Cell Loss After Pneumatic Retinopexy for the Repair of Primary Rhegmatogenous Retinal Detachment
|
N/A | |
Not yet recruiting |
NCT01647373 -
Axial Length Change in Eyes Treated by Silicone Sponge Scleral Buckling
|
N/A | |
Completed |
NCT01068379 -
Clinical Trial of Cryotherapy Versus Postoperative Laser Photocoagulation
|
Phase 3 | |
Not yet recruiting |
NCT06468397 -
Acute Retinal Detachment Repair With the iSeelr^TM Retinal Detachment Repair System
|
N/A | |
Not yet recruiting |
NCT06425419 -
The Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy
|
Phase 1 | |
Recruiting |
NCT06056596 -
Lamivudine and Plasma Markers of Inflammation in Retinal Detachment
|
Early Phase 1 | |
Completed |
NCT01343134 -
Anatomical and Functional Macular Changes in Retinal Detachment
|
N/A | |
Recruiting |
NCT05588037 -
Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery
|
N/A | |
Completed |
NCT03542162 -
Healaflow Patch for the Treatment of Rhegmatogenous Retinal Detachment
|
N/A |