Subretinal Hemorrhage and Exudative Maculopathy Clinical Trial
Official title:
Perfluorocarbon Gases for the Repair of Retinal Detachments.
Subretinal hemorrhage in the macula causes a significant loss of vision. This hemorrhage can be displaced by the use of a small volume of pure perfluorocarbon gas injected into the vitreous, which expands to a 40% gas bubble in the eye. When the patient gazes 40 to 60 degree below the horizontal, the gas bubble covers the hemorrhage and gravity displaces it rapidly. This position of gaze is easier for the patient than the face down position traditionally recommended.A vector of gravity force tangential to the sclera brings about this displacement. The procedure can improve vision quickly, reduce unwanted degenerative changes in the macula because of the persistent macular hemorrhage and improves the chances of treating of the underlying cause for the subretinal hemorrhage by laser or other means.
Status | Recruiting |
Enrollment | 25 |
Est. completion date | June 2009 |
Est. primary completion date | June 2009 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 20 Years to 95 Years |
Eligibility |
Inclusion Criteria: - Diminished vision secondary to subretinal hemorrhage in the macula or exudative maculopathy. Exclusion Criteria: - Patient unable to maintain gaze position for 20 minutes every waking hour for 7 days. - Patient unable to sleep on their side or with head elevated 40 degrees. |
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | New York Presbyterian Hospital | New York | New York |
Lead Sponsor | Collaborator |
---|---|
Weill Medical College of Cornell University | The Edward Grayson Fund for Retinal Research |
United States,
Johnson MW. Pneumatic displacement of submacular hemorrhage. Curr Opin Ophthalmol. 2000 Jun;11(3):201-6. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Displacement of Subretinal Hemorrhage | 7 days after gas injection | Yes | |
Secondary | Improvement in visual acuity | 7 days after gas injection | No |