Wet Age-Related Macular Degeneration Clinical Trial
Official title:
A Randomized, Double-Masked, Multicenter, Phase I/II Study of the Safety of PTK787 Administered to Patients With Predominantly Classic , Minimally Classic or Occult With no Classic Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration
This study evaluates the tolerability and safety of 3 months treatment with PTK787 tablets
given daily. It also explores the efficacy of the compound in patients with wet age-related
macular edema.
In Cohort 1 verteporfin/PDT is the active control. The protocol was amended to reflect the
current standard of care for AMD. As a result, ranibizumab is the active control for Cohort
2.
n/a
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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