Postoperative Nausea and Vomiting Clinical Trial
Official title:
A Randomized, Double-Blind, Active Comparator-Controlled, Parallel-Group Study, Conducted Under In-House Blinding Conditions, to Examine the Safety, Tolerability, and Efficacy of 2 Doses of Aprepitant for the Prevention of Postoperative Nausea and Vomiting
The purpose of this study is to assess the safety and efficacy of 2 doses of an approved drug for a new indication in the prevention of postoperative nausea and vomiting in patients receiving general anesthesia for open abdominal surgery requiring overnight hospital stay.
The duration of treatment is 4 weeks. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04466046 -
The Effect on Anxiolytics With Type of Antiemetic Agents on Postoperative Nausea and Vomiting in High Risk Patients
|
||
Completed |
NCT03139383 -
Dextrose Containing Fluid and the Postoperative Nausea and Vomiting in the Gynecologic Laparoscopic Surgery
|
N/A | |
Recruiting |
NCT04069806 -
Preoperative Oral Carbohydrate for Nausea and Vomiting Prevention During Cesarian Section
|
N/A | |
Completed |
NCT04043247 -
Transcutaneous Electrical Acupoint Stimulation for Prevention of Postoperative Nausea and Vomiting
|
N/A | |
Terminated |
NCT01975727 -
Dexamethasone for the Treatment of Established Postoperative Nausea and Vomiting
|
Phase 2 | |
Completed |
NCT03662672 -
Rib Raising for Post-operative Ileus
|
N/A | |
Recruiting |
NCT05375721 -
Prevention of PONV With Traditional Chinese Medicine
|
N/A | |
Completed |
NCT02480088 -
Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism
|
Phase 4 | |
Recruiting |
NCT06137027 -
Cannabidiol Oil Extract for Prevention of Postoperative Nausea and Vomiting
|
Early Phase 1 | |
Not yet recruiting |
NCT05529004 -
A 6 Months Double Blind Trial to Prevent PONV in Laparoscopic Cholecystectomy
|
Phase 2 | |
Completed |
NCT02944942 -
Risk Factors for Postoperative Nausea/Vomiting
|
N/A | |
Recruiting |
NCT02571153 -
Low Doses of Ketamine and Postoperative Quality of Recovery
|
Phase 4 | |
Completed |
NCT02449291 -
Study of APD421 as PONV Treatment (no Prior Prophylaxis)
|
Phase 3 | |
Completed |
NCT02550795 -
Dexmedetomidine or Dexmedetomidine Combined With Dexamethasone on Postoperative Nausea and Vomiting in Breast Cancer
|
N/A | |
Recruiting |
NCT01442012 -
Utility of Acupuncture in the Treatment of Postoperative Nausea and Vomiting in Ambulatory Surgery
|
N/A | |
Completed |
NCT01478165 -
Comparison of TIVA (Total Intravenous Anesthesia) and TIVA Plus Palonosetron in Preventing Postoperative Nausea and Vomiting
|
N/A | |
Unknown status |
NCT01268748 -
Single Port Versus Four Ports Laparoscopic Cholecystectomy and Early Postoperative Pain
|
N/A | |
Completed |
NCT02143531 -
Intravenous Haloperidol Versus Ondansetron for Treatment of Established Post-operative Nausea and Vomiting
|
Phase 4 | |
Completed |
NCT00734929 -
Aprepitant With Dexamethasone Versus Ondansetron With Dexamethasone for PONV Prophylaxis in Patients Having Craniotomy
|
Phase 4 | |
Withdrawn |
NCT00151099 -
Safety of Preoperative Oral Administration of a High Caloric Drink With Protein
|
Phase 4 |