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NCT ID: NCT06461182 Recruiting - Clinical trials for Indolent B-Cell Non-Hodgkin Lymphoma

Ga-68-CXCR4 PET/CT in Indolent B-cell Lymphoma

PentixaFor
Start date: April 29, 2024
Phase: Phase 2
Study type: Interventional

This study explores the efficacy of Ga-68-PentixaFor PET/CT in detecting, assessing treatment response, and monitoring the risk of aggressiveness in indolent B-cell lymphoma. The background introduces CXCR4 and discusses its role in cancer research. Currently, FDG-PET is the primary imaging tool for lymphoma staging, but it lacks diagnostic accuracy for low-grade lymphomas. Ga-68-PentixaFor PET demonstrates promising detection capabilities across various lymphomas, suggesting its potential as a superior imaging modality for low-grade lymphomas.

NCT ID: NCT06461169 Not yet recruiting - COPD Clinical Trials

The Effect of Stress Ball on COPD Patients Receiving Noninvasive Mechanical Ventilation Support

Start date: June 15, 2024
Phase: N/A
Study type: Interventional

The aim of this randomised controlled trial was to investigate the effect of a stress ball on pain, anxiety and physiological parameters in Chronic Obstructive Pulmonary Disease (COPD) patients on non-invasive mechanical ventilation (NIMV).

NCT ID: NCT06461156 Not yet recruiting - Clinical trials for Locally Advanced or Metastatic NSCLC

A Study of HS-10504 in Patients With Advanced or Metastatic Non-Small-Cell Lung Cancer(NSCLC)

Start date: June 30, 2024
Phase: Phase 1
Study type: Interventional

HS-10504 is a fourth-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor targeting EGFR C797S mutation. This study will evaluate the safety, tolerability, pharmacokinetics and efficacy of HS-10504 in Chinese locally advanced or metastatic NSCLC.

NCT ID: NCT06461013 Recruiting - Clinical trials for Hemiplegia and/or Hemiparesis Following Stroke

The Effect of Blood Flow Restriction Training on Lower Limb Motor Function in Stroke Patients With Hemiplegia

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

flow restriction training combined with routine rehabilitation training can promote the recovery of lower limb muscle strength on the hemiplegic side of stroke patients, improve the lower limb motor function of patients, and further improve their daily life and walking ability. It provides a new treatment method for stroke patients with hemiplegia that leads to lower limb function loss and activity disorder, and the therapy also has the advantages of simple operation, high safety, good patient compliance and low cost, which is worthy of further clinical research and promotion.

NCT ID: NCT06460571 Recruiting - Clinical trials for Percutaneous CORONARY INTERVENTION

Cardiac Rehabilitation With and Without Delorme Technique of Progressive Resisted Exercises in Patients of Post PCI.

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

To find the effect of cardiac rehabilitation program with and without progressive resisted exercises on patients after acute stage of PCI with at least 8 weeks history. It is a randomized clinical trial using convenient sampling technique. Randomly assign participants into two groups: An intervention group receiving Delorme progressive resisted exercise along with cardiac rehab and a control group undergoing standard cardiac rehabilitation alone. In Group A, Delorme technique will involve a 10-repetition max of aerobic and resistance exercises along with cardiac rehab. Seven different exercises will be performed in 3 sets of 10-repetition max. The control group will not be performing any type of training but will undergo cardiac rehab alone. Data will be analyzed using t test and SPSS 21 will be used for data collection. Age group will be from ≥70 years with patient undergoing dyspnea along with recent history of primary diseases. Data will be collected from Bethania Hospital, Sialkot through tools like the 6-minute walk test, Rose Angina questionnaire or settle angina questionnaire, quality of life scale (QOLFS), and Modified Borg dyspnea scale.

NCT ID: NCT06460441 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea Hypopnea Syndrome

Comparison of the SUNRISE© Device With Ventilatory Polygraphy for the Diagnosis of Obstructive Sleep Apnea Hypopnea Syndrome: Collection of Preliminary Data

SUNPV
Start date: June 17, 2024
Phase:
Study type: Observational

Additional data on screening for obstructive sleep apnea/hypopnea syndrome (OSAHS) in patients with co-morbidities, such as diabetics and those with chronic respiratory diseases would enable current recommendations to evolve, with a view to promoting the widespread use of simplified techniques for OSAHS screening, particularly in patients with cardiorespiratory co-morbidities. The primary objective of this observational multicentric pilot study is to compare the performance of the Sunrise® medical device with that of ventilatory polygraphy as part of routine screening for OSAHS in diabetic patients followed up in the diabetology department of the Strasbourg University Hospital, and in patients followed up in the pneumology consultation department of Mulhouse Hospital (GHRMSA).

NCT ID: NCT06460207 Not yet recruiting - Cognitive Training Clinical Trials

Neurofeedback Removal of Emotional Information From Mind

remtrain
Start date: September 2024
Phase: N/A
Study type: Interventional

This project will examine whether individuals can be trained, using real-time feedback about brain function during neuroimaging, to effectively remove thoughts from mind by providing them with a sense of what it feels like to successfully remove a thought.

NCT ID: NCT06459869 Not yet recruiting - Clinical trials for Locally Advanced Rectal Cancer (LARC)

NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer

FORTRESS
Start date: November 15, 2024
Phase: Phase 1
Study type: Interventional

The FORTRESS trial (NG-350A-03) is an open-label, single-arm, and multicentre trial of NG-350A in combination with chemoradiotherapy (CRT) in adult patients with locally advanced rectal cancer (LARC) and at least one risk factor for local or distant recurrence.

NCT ID: NCT06459622 Not yet recruiting - Clinical trials for Chronic Rhinosinusitis With Nasal Polyps

Predictive Factors in Chronic Rhinosinusitis With Nasal Polyps

Start date: July 2024
Phase: N/A
Study type: Interventional

The study will be conducted to identify factors predicting the response of chronic rhinosinusitis with nasal polyps ( CRSwNP) to oral corticosteroids.

NCT ID: NCT06459193 Not yet recruiting - Clinical trials for Peripheral Neuropathy Due to Chemotherapy

Trimetazidine Efficacy in Attenuating Paclitaxel-Induced Peripheral Neuropathy

Start date: June 16, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

This proof-of-concept study evaluated the effect of Trimetazidine on the incidence of paclitaxel-induced peripheral neuropathy in patients with breast cancer.