Jogging in the Change of Osteoporosis

Osteoporosis Clinical Trial

Official title:

Jogging in the Change of Osteoporosis

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03359317
• Other study ID #: PKUPH-JGO
• Status: Not yet recruiting
• Phase: N/A
• First received: November 26, 2017
• Last updated: November 29, 2017
• Start date: February 20, 2018
• Est. completion date: January 30, 2019

Study information

• Verified date: November 2017
• Source: Peking University People's Hospital
• Contact: Peixun Zhang, MD
• Phone: 15210802766
• Email: 875274428[@]qq.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To test the changes in osteoarthritis according to the X-rays, and changes in bone quality before and 1 or more years after beginning the jogging

Description:

Patients in this research are given an entry Bone Densitometry（DEXA）scan and are required to advance from 3-minute jogging a day to 10-minute level in daily practice for 1 year as instructed. After 1 year, subsequent DEXA scans are recorded. Interested participants are also encouraged to have hip and spine X-rays, and bone quality studies on study entry and two years later. Actual subject participation, intercurrent illnesses, fractures and changes in medication are self-monitored. Results are calculated by change in bone mineral density in the lumbar spine, hips and femurs by the DEXA scan in the study. Dose-response relationships between the amount of jogging and bone mineral density are sought. Jogging-related fractures and other adverse effects are also noted.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 500
• Est. completion date: January 30, 2019
• Est. primary completion date: January 30, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 50 Years to 60 Years

Eligibility

Inclusion Criteria:

Past DEXA scan and, all within 6 months of study entry, DEXA scan and normal values for:

Metabolic panel, TSH, PTH, ESR (or CRP), Vitamin D 25 hydroxy, Vitamin D 1,25 dihydroxy, Urine NTX

Exclusion Criteria:

Known metabolic bone disease such as osteogenesis imperfecta, current treatment with steroids, chemotherapy, or currently healing fractures of lumbar spine, hips or femurs, severe heart disease

Related Conditions & MeSH terms

• Osteoporosis

Intervention

Behavioral:
• jogging
Jogging as instructed for 1 year

Locations

Country	Name	City	State
n/a

Sponsors (4)

Lead Sponsor	Collaborator
Peking University People's Hospital	Chongqing Zhongshan Hospital, Shenzhen Sun Yat-sen Cardiovascular Hospital, Wujin People's Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	DEXA T-score	Bone mineral density change in spine, hip and femur after 1 year of jogging	1 year
Secondary	Number of fractures	Number of fractures occurring while in study	1 year