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PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)

Osteoporosis Clinical Trial

Official title:
PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)

Clinical Trial Summary

Declines in serum calcium during exercise may cause increases in markers of bone resorption. This study will determine if preventing the decline serum ionized calcium experienced at the onset of exercise through the use of a "calcium clamp" also prevents increases in blood biomarkers associated with bone resorption.

Clinical Trial Description

Participants will undergo two identical walking exercise sessions on a treadmill. One session will occur until continuous calcium infusion and the other will be under continuous saline infusion. C-telopeptide, parathyroid hormone, total calcium, and serum ionized calcium will be monitored to distinguish differences in bone activity under the two conditions. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02580604
Study type Interventional
Source University of Colorado, Denver
Contact Sarah J Wherry, PhD
Phone 303-724-1927
Email sarah.wherry@ucdenver.edu
Status Recruiting
Phase Early Phase 1
Start date November 2015
Completion date September 30, 2024
View Details
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