Osteoporosis Clinical Trial
Official title:
Patho-physiology of Osteoporosis in Patients With Chronic Obstructive Pulmonary Disease (COPD)
The main objective is to study important factors in the patho-physiology of osteoporosis in patients with COPD. Therefore, the investigators will study biological markers in plasma and urine and correlate them to markers of bone turnover and clinical data.
Rationale:
Chronic obstructive pulmonary disease (COPD) is defined as a preventable and treatable
disease with significant extrapulmonary effects. Osteoporosis is recognized as one of these
extrapulmonary consequences. It results in increased risk of fracture and thereby an
increased morbidity and mortality. Nowadays it is believed that the patho-physiology of
osteoporosis is multi-factorial. However, which factors are most important in patients with
COPD is still not clear.
Objective:
The main objective is to study important factors in the patho-physiology of osteoporosis in
patients with COPD. Therefore, we will study biological markers in plasma and urine and
correlate them to markers of bone turnover and clinical data.
Study design:
The present study will be an observational, cross-sectional study.
;
Observational Model: Cohort, Time Perspective: Cross-Sectional
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