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NCT00443716 Clinical Trial

Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women

Osteoporosis Clinical Trial

Official title:
Determination of Adipocyte Parameters in Iliac Crest Biopsies From Post Menopausal Women

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00443716
Other study ID # 05-004111
Secondary ID 21b85
Status Completed
Phase N/A
First received March 5, 2007
Last updated January 14, 2010
Start date April 1985
Est. completion date April 1989

Study information
Verified date January 2010
Source Mayo Clinic
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Interventional

Clinical Trial Summary

To evaluate the effect of estrogen treatment on adipocytic and osteoblastic parameters by histomorphometrically measuring adipocyte volume (AV/TV) and adipocyte numbers in goldner's stained iliac crest bone biopsy specimens collected from subjects recruited in the study (IRB number 21B85). The adipocytic parameters will be then correlated with osteoblastic parameters obtained previously during the course of the initai study involving the effect of transdermal estrogen on bone turnover in postmenopausal osteoporotic women.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date April 1989
Est. primary completion date April 1989
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 30 Years and older
Eligibility Post-menopausal osteoporotic women

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• estrogen

Locations
Country Name City State
United States Mayo Clinic Rochester Minnesota

Sponsors (1)
Lead Sponsor Collaborator
Mayo Clinic

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary efficacy of estraderm treatment on osteoporotic women
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