Osteoporosis Clinical Trial
OBJECTIVES: I. Compare whether the bone tissue in the spine and hip improves in patients
with adult onset growth hormone deficiency treated with growth hormone (GH) vs placebo.
II. Determine whether the blood samples of these patients show evidence of beneficial bone
effects after treatment with GH.
III. Compare the quality of life of these patients treated with these 2 regimens.
IV. Determine the side effects of GH in these patients.
Status | Completed |
Enrollment | 72 |
Est. completion date | |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- - Diagnosis of adult onset growth hormone deficiency --Patient Characteristics-- - Not pregnant or nursing - Negative pregnancy test - Fertile patients must use effective contraception |
Allocation: Randomized, Masking: Double-Blind, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
United States | Massachusetts General Hospital | Boston | Massachusetts |
United States | Case Western Reserve University | Cleveland | Ohio |
United States | University of Pennsylvania School of Medicine | Philadelphia | Pennsylvania |
United States | Oregon Health Sciences University | Portland | Oregon |
United States | Rhode Island Hospital | Providence | Rhode Island |
United States | Mayo Clinic | Rochester | Minnesota |
United States | St. Louis University Health Sciences Center | Saint Louis | Missouri |
Lead Sponsor | Collaborator |
---|---|
National Center for Research Resources (NCRR) | University of Pennsylvania |
United States,
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