Osteoporosis Fracture Clinical Trial
Official title:
Osteoporosis and Fall Prevention With Multiple Interventions in the Metropolitan Area
OBJECTIVES To determine the effects of 3 exercise interventions on sarcopenic indices among
community-dwelling older adults with high osteoporotic fracture risks.
MATERIAL AND METHOD The current study enrolled subjects who screened high risk of fall,
osteoporosis/fracture by standardized questionnaires or FRAX. Subjects at the National Taiwan
University Hospital Bei-Hu Branch (NTUHBB) were randomized into integrated care group (ICG,
target n=50) and muscle training group (MTG, target n=50). Subjects from Lingko Chang Gung
Memorial Hospital (LCGMH) were all assigned into X-box group (XBG, target n=30). All
participants received a CD-ROM and a one education on osteoporosis, sarcopenia, frailty, fall
prevention, nutrition, and coping strategy and another hour of professional led exercise
program. ICG subjects received once weekly group exercise while MTG subjects received twice
weekly machine-based resistence training on major muscle groups. XBG subjects rececived twice
weekly exercise with X-box based programs. Major outcomes were muscle mass (measured by
bio-impedance analysis), grip strength, walking speed, and lower leg extension power at
baseline and after 12-weeks of intervention.
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