Enthesitis in Patients With Knee Osteoarthritis

Osteoarthritis Clinical Trial

Official title:

Prevalence of Knee Cap Enthesitis in Patients With Knee Osteoarthritis, Cross Sectional Ultrasonographic Study.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03897829
• Other study ID #: aswu/320/1/19
• Status: Completed
• Start date: March 29, 2019
• Est. completion date: May 30, 2019

Study information

• Verified date: June 2019
• Source: Al-Azhar University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The current study was conducted to estimate the prevalence of knee cap enthesitis in patients with knee osteoarthritis and its relation to knee function.

Description:

The current study will based on a cross sectional hospital-based survey, conducted among patients with knee osteoarthritis , Knee will assessed for the following items in both sides while Patient lying supine with the knee flexed 40 degrees:

1. Superior pole of the patella - quadriceps tendon enthesis: ● Quadriceps tendon thickness >6.1 mm ● Suprapatellar bursitis ● Superior pole of patella erosion ● Superior pole of patella enthesophyte.

2. Inferior pole of the patella - proximal patellar ligament enthesis: ● Patellar ligament thickness >4 mm ● Inferior pole of patella erosion ● Inferior pole of patella enthesophyte.

3. Tibial tuberosity - distal patellar ligament enthesis ● Patellar ligament thickness >4 mm ● Infrapatellar bursitis ● Tibial tuberosity erosion ● Tibial tuberosity enthesophyte.

Knee functional status was assessed using Knee injury and Osteoarthritis Outcome Score (KOOS) scale for Pain, other Symptoms, Activities of Daily Living (ADL), Sport and Recreation Function (Sport/Rec) and knee-related Quality of Life (QOL). Low knee function was considered if the patient had score 50 or more in any KOOS scale parameter.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 200
• Est. completion date: May 30, 2019
• Est. primary completion date: May 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Primary Knee OA diagnosed according to: American College of Rheumatology Radiologic Criteria for Knee Osteoarthritis.

• Kellegren - Lawrance scale grade II.

• On regular treatment by analgesics, or NSAIDS either topical or systemic.

Exclusion Criteria:

• Recent Knee trauma or intra-articular procedures.

• Previous knee surgery.

• Inflammatory joint diseases, as rheumatoid arthritis, crystal arthritis, and spondyloarthropathy

• chronic systemic diseases that could affect patient functional ability; e.g renal, liver, cardiac impairment, or neurological disorder.

Related Conditions & MeSH terms

• Osteoarthritis
• Osteoarthritis, Knee

Locations

Country	Name	City	State
Egypt	Al-Azhar Faculty of medicine, Rheumatology Department	Cairo
Egypt	Al-Azhar university hospitals	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Al-Azhar University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of knee cap enthesitis in patients with knee osteoarthritis	Detection of the prevalence	two months