Osteoarthritis Clinical Trial
— ORTHOSIMV1Official title:
Medical Imaging of the Musculoskeletal System Before and After Surgery for the Generation of Customized Biomechanical Models
The objective of this study is to design a library of biomechanical musculoskeletal models of patients before and after surgery. These models will be evaluated to analyze the support they can provide for virtual surgical planning in orthopedics.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | October 1, 2021 |
Est. primary completion date | March 1, 2021 |
Accepts healthy volunteers | |
Gender | All |
Age group | 20 Years to 65 Years |
Eligibility |
Inclusion criteria: - Men or women aged 20 to 65 years - Patients who have had orthopaedic surgery - Presence in the file of a preoperative CT scan and/or magnetic resonance imaging (MRI) - Presence in the file of a CT scan and/or MRI postoperatively at a distance from the operation (at least 4 weeks) - Presence in the file of an operating report describing the procedure in detail with access routes, operating times, type of equipment and possible complications. - Patient who has authorized the anonymous use of data from his pre and post surgical examinations - Patient who is a member of a social security organisation Criteria for non-inclusion: - Patient who has expressed his refusal to use his medical data - Minor, patient under guardianship, inability to receive information and express consent - Pregnant women - Non-affiliation to a social security scheme (beneficiary or beneficiary) - Examinations of images that do not allow 3D reconstruction of structures (poor resolution or type of sequence) - Incomplete operating report not allowing the understanding of the steps of the surgery. - Surgical report describing surgery that does not represent the usual procedures performed. |
Country | Name | City | State |
---|---|---|---|
France | Laboratoire CNRS TIMC IMAG | La Tronche | Grenoble Alpes University - CNRS UMR |
Lead Sponsor | Collaborator |
---|---|
Centre d'Investigation Clinique et Technologique 805 | Fondation Garches, Fondation pour la Recherche Médicale, TIMC-IMAG |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Bones volume assessment | Comparison of volume of bone pieces in mm3 | 20 days | |
Primary | Soft tissue volume assessment | Volume comparison of soft tissue envelope in mm3 | 20 days | |
Primary | Relative positions of bones | Comparison of the relative positions of bones relative to each other in degrees | 10 days | |
Secondary | Biomechanical response | the convergence of the numerical simulation performed from the reconstructed model. measurement of the Stress in Nm-2 and the strains (Strain has no units because it is a ratio of lengths) |
2 days |
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