Osteoarthritis Clinical Trial
Official title:
Efficacy and Cost-effectiveness of Intra-Articular Ketorolac Injection for Knee Osteoarthritis: A Randomized, Controlled, Double-Blinded Study
Hypothesis: Ketorolac injection is a cost-effective adjunct in the nonoperative treatment of
knee osteoarthritis (OA) compared to steroids and viscosupplementation.
Aims/objectives: The objective of this randomized, controlled, double-blinded, prospective
study is to assess the efficacy and cost-effectiveness of knee injection with ketorolac in
the nonsurgical management of symptomatic OA compared to injections with corticosteroids and
viscosupplements.
The purpose of this research study is to examine the effectiveness of intra-articular (inside the joint) ketorolac injection compared to injection with either corticosteroid or hyaluronic acid for the treatment of painful knee osteoarthritis. Patients will be randomly assigned to receive either ketorolac (a nonsteroidal anti-inflammatory drug, methylprednisolone (a steroid), hyaluronic acid (a substance that is naturally present in the human body). ;
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