Osteoarthritis Clinical Trial
Official title:
A Cluster Randomised Trial to Measure the Impact of a Free Distribution of Paracetamol to Osteoarthritic Patients on Non-steroidal Anti-inflammatory Drugs (NSAID) and Proton Pump Inhibitors (PPI) Prescription
Paracetamol is recommended as first line treatment for pain control in osteoarthritis, but
it is not included in list of drugs than can be prescribed in charge of National Health
System by General Practitioners. The hypothesis is that removing this economical barrier the
investigators can decrease the prescription of NSAID and of the Proton Pump Inhibitors
(PPI), often given for gastric bleeding prophylaxis in NSAID chronic users. As secondary
outcome, opioids use was also monitored to see.
Aim of the study is to test if allowing prescription of free paracetamol decreases the
prescription of NSAID in osteoarthritic patients.
The trial was conducted in two primary care units of the province of Reggio Emilia. The units have about 34.000 inhabitants. In this units 16 General Practitioners are active, the average beneficiaries per General Practitioner are 1500, about one fourth over 65 years old. ;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Health Services Research
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