Osteoarthritis Clinical Trial
Official title:
The Effect of Intra-articular Pulsed Radiofrequency in Osteoarthritis
Pulsed radiofrequency (PRF) is designed to alleviate pain by delivering an electrical field
and heat bursts at a temperature less than 42°C to neural tissue. In contrast with
conventional radiofrequency, PRF is controlled below 42°C without damage to nerves and many
studies have shown its benefits in pain relief for certain kinds of chronic pain conditions.
For lessening pain of certain joint arthropathy, the direct nerve block by application of
PRF is difficult and complicated because the supplying nerve of joint is complex or small.
Hence, some authors perform intra-articular PRF on the chronic painful joint for example,
knee osteoarthritis, atlantoaxial joint, cervical facet joint sacroiliac joint, scapholunate
and shoulder joint and the excellent long-term effects are reported.
The purpose of this study is to investigate the effect of intra-articular PRF in
osteoarthritis.
Pulsed radiofrequency (PRF) is designed to alleviate pain by delivering an electrical field
and heat bursts at a temperature less than 42°C to neural tissue. In contrast with
conventional radiofrequency, PRF is controlled below 42°C without damage to nerves and many
studies have shown its benefits in pain relief for certain kinds of chronic pain conditions.
For lessening pain of certain joint arthropathy, the direct nerve block by application of
PRF is difficult and complicated because the supplying nerve of joint is complex or small.
Hence, some authors perform intra-articular PRF on the chronic painful joint for example,
knee osteoarthritis, atlantoaxial joint, cervical facet joint sacroiliac joint, scapholunate
and shoulder joint and the excellent long-term effects are reported.
However, the definite effect of intra-articular PRF for osteoarthritis from current
published studies are insufficiently proved because of small patient numbers and lack of
placebo-controlled design. The purpose of this study is to investigate the effect of
intra-articular PRF in osteoarthritis.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04657926 -
A Trial of APPA in the Treatment of Knee Osteoarthritis
|
Phase 2 | |
Completed |
NCT02536833 -
A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects
|
Phase 2 | |
Completed |
NCT03014037 -
Comparing Mesenchymal Stem Cell Counts in Unilateral vs. Bilateral Posterior Superior Iliac Spine Bone Marrow Aspiration
|
N/A | |
Recruiting |
NCT05937542 -
A Qualitative Investigation of CLEAT Participants
|
||
Completed |
NCT03644615 -
A Mindfulness Program (MBSR) in the Management of Symptomatic Hip and Knee Osteoarthritis
|
N/A | |
Recruiting |
NCT06061367 -
Muscles Strength and Gait Parameteres After TKA
|
||
Withdrawn |
NCT04976972 -
A Comparison of Patients Receiving a Total Knee Replacement With Robotic Assistance or With Conventional Instrumentation
|
N/A | |
Completed |
NCT05496205 -
A SAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers
|
Phase 1 | |
Completed |
NCT03850665 -
Comparison of Functional Outcome in Patients After Hip Arthroplasty Depending on Surgical Approach
|
N/A | |
Completed |
NCT02826902 -
Effect of Anesthesia on Quality of Recovery in Patients Undergoing Correctional Tibial Osteotomy - A Randomized Controlled Trial
|
N/A | |
Completed |
NCT04402502 -
Dynamic 4DCT to Examine Wrist Carpal Mechanics
|
N/A | |
Completed |
NCT02923700 -
Leukocyte-rich PRP vs Leukocyte-poor PRP for the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial
|
Phase 4 | |
Completed |
NCT04564053 -
Study of Safety, Tolerability and Pharmacokinetics of LNA043 in Japanese Osteoarthritis Participants
|
Phase 1 | |
Completed |
NCT05070871 -
A Clinical Trial Investigating the Effect of Salmon Bone Meal on Osteoarthritis Among Men and Women
|
N/A | |
Not yet recruiting |
NCT05036174 -
Diphenhydramine Ointment for Knee Osteoarthritis
|
N/A | |
Recruiting |
NCT02912429 -
Onlay vs. Inlay Patellofemoral Arthroplasty
|
N/A | |
Recruiting |
NCT02666443 -
Low Dose Dexamethasone in Supraclavicular Blocks
|
N/A | |
Active, not recruiting |
NCT02723929 -
Effects of tDCS and tUS on Pain Perception in OA of the Knee
|
||
Withdrawn |
NCT02921594 -
Kinematic Comparison of Vanguard XP and Vanguard CR Total Knee Arthroplasties
|
N/A | |
Terminated |
NCT02820766 -
Journey II BCS CMS Total Knee System Compared to Other PS Total Knee Systems in PT Setting
|
N/A |