Vascular Occlusion in Patients With Osteoarthritis

Osteoarthritis Clinical Trial

Official title:

Effects of Strength Training Associated With Vascular Occlusion in Patients With Knee Osteoarthritis

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT01483131
• Other study ID #: vascular occlusion and OA
• Status: Recruiting
• Phase: N/A
• First received: November 29, 2011
• Last updated: February 27, 2014
• Start date: November 2011
• Est. completion date: December 2014

Study information

• Verified date: February 2014
• Source: University of Sao Paulo
• Contact: Rodrigo Ferraz, Msc
• Phone: 55 11 8122 1203
• Email: ferraz[@]email.com
• Is FDA regulated: No
• Health authority: Brazil: National Committee of Ethics in Research
• Study type: Interventional

Clinical Trial Summary

Resistance exercise plus vascular occlusion may induce greater improvements in strength and muscle mass than resistance training alone. The investigators speculate this training strategy could be beneficial in patients with osteoarthritis.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 45
• Est. completion date: December 2014
• Est. primary completion date: November 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 50 Years to 65 Years

Eligibility

Inclusion Criteria:

• Postmenopausal women

• BMI <39

• Knee Ostearthritis type II and III

• VAS (visual analogue scale) between 2 and 8

Exclusion Criteria:

• Hip osteoarthritis

• Use of NSAID

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Osteoarthritis

Intervention

Other:
• Exercise training
12 weeks of resistance training twice a week.
• Resistance training with vascular occlusion
12 weeks of resistance training with vascular occlusion twice a week

Locations

Country	Name	City	State
Brazil	University of Sao Paulo -School of Medicine - Clinical Hospital	Sao Paulo

Sponsors (1)

Lead Sponsor	Collaborator
University of Sao Paulo

Country where clinical trial is conducted

Brazil, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	muscle strength		12 weeks	No
Secondary	Quality of Life		12 weeks	No