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A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.

Osteoarthritis Thumb Clinical Trial

Official title:
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.

Clinical Trial Summary

This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.

Clinical Trial Description

The aim of this study is to evaluate if high-concentration PRP injection decreases pain and disability in patients with thumb base osteoarthritis in the short-term and compare the effect to placebo.90 patients will be inlcuded (45+45). The primary outcome is pain on load (numerical rating scale) after 6 months. Patient-rated outcome measures, pinch grip and key pinch, range of motion of the CMC.1 joint will be assessed before treatment and at 3, 6 and months after the injection. Participants and assessors will be blinded. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06193499
Study type Interventional
Source Karolinska Institutet
Contact Maria Wilcke, MD, PhD
Phone +46708294613
Email maria.wilcke@regionstockholm.se
Status Recruiting
Phase N/A
Start date January 17, 2024
Completion date June 30, 2027
View Details
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