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Osteoarthritis, Shoulder clinical trials

View clinical trials related to Osteoarthritis, Shoulder.

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NCT ID: NCT06171542 Active, not recruiting - Clinical trials for Shoulder Osteoarthritis

Efficacy of a Single Image Guided Injection of CTM for Glenohumeral Arthritis

HC22-1
Start date: December 22, 2022
Phase: Phase 1
Study type: Interventional

CTM Biomedical markets and distributes decellularized particulate human placental connective-tissue matrix products, intended solely for homologous use to supplement or replace damaged or inadequate connective-tissue. These are structural tissue allografts processed according to the criteria contained in 21CFR 1271.10(a) for regulation solely under section 361 of the Public Health Service Act. The goal of this study is to determine the success rate of a single, image guided glenohumeral CTM injection (for radiographically confirmed glenohumeral osteoarthritis at follow up intervals of 1, 2, 3, 4, 6, 9, and 12 months. This will be measured using the Likert Pain Scale (LPS) and Oxford Shoulder Score (OSS). Secondary goals are to identify if certain demographic or imaging factors exist that predict early symptom recurrence requiring additional intervention, defined as a second connective tissue matrix injection, a subsequent corticosteroid injection, or arthroplasty.

NCT ID: NCT06078865 Recruiting - Clinical trials for Osteoarthritis Shoulder

FX Shoulder Prospective Clinical Study

Start date: March 31, 2021
Phase:
Study type: Observational [Patient Registry]

Prospective Multi-Center Registry on study subjects with implanted devices marketed and legally commercialized in the USA by FX Shoulder Solutions.

NCT ID: NCT06077942 Recruiting - Clinical trials for Osteoarthritis Shoulder

FX Shoulder Solutions Retrospective / Prospective Clinical Study

Start date: December 6, 2022
Phase:
Study type: Observational

Subjects implanted with the shoulder replacement medical devices manufactured by FX Shoulder Solutions and distributed by FX Shoulder Solutions.

NCT ID: NCT06032416 Not yet recruiting - Rotator Cuff Tears Clinical Trials

DenCT Shoulder Bone Quality Evaluation

Start date: September 2024
Phase: N/A
Study type: Interventional

The objective of the study is to evaluate the preoperative bone quality assessment based on CT to later establish a scale for the decision of stemless shoulder arthroplasty.

NCT ID: NCT05868148 Recruiting - Rotator Cuff Tears Clinical Trials

Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study

SiD
Start date: October 20, 2023
Phase:
Study type: Observational

The goal of the Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study is to collect safety and performance data on the commercially available Shoulder iD™ Primary Reversed Glenoid device. The study will learn about standard device use in adult patients who have a functional deltoid muscle and massive and non-repairable rotator cuff tear. The main questions it aims to answer are: - What is the average improvement in patient-reported shoulder function after 2 years when compared to before the surgery, and - What is the rate of surgical revisions needed over a 10 year period Patients will be asked to will be asked to regularly attend their check-up visits with their surgeon (including having x-rays or CT images taken to check their shoulder and implant), to complete questionnaires to report how their shoulder is doing, and to tell their surgeon when they notice any changes.

NCT ID: NCT05861960 Recruiting - Clinical trials for Osteoarthritis Shoulder

Endogenous Pain Modulation Study

EPM
Start date: March 4, 2024
Phase:
Study type: Observational

Rationale: Although most patients experience significant pain relief after total shoulder arthroplasty (TSA), pain persists for some patients even after surgery. The endogenous pain system may be involved in persisting postoperative pain in total knee arthroplasty (TKA) and total hip arthroplasty (THA) patients, but this has never been studies for TSA patients. Furthermore, psychological factors and coping strategies may also be of interest but have not yet been extensively studied in TSA patients. Objective: The primary objective is to explore whether central sensitization and/or abnormal CPM responses are present in (a subgroup of) patients who will receive shoulder arthroplasty for osteoarthritis, and whether shoulder arthroplasty produces change in these measures of the endogenous pain modulatory system. The secondary objective, in case patients with altered endogenous pain modulation are found, is to explore if change in pain over time, psychological factors and coping strategies differ between patients with and without altered pain modulation. Study design: An exploratory prospective observational cohort study. Study population: Patients (age 18 years or older) who are scheduled to undergo shoulder arthroplasty for osteoarthritis, at the Reinier Haga Orthopaedic Centre. Intervention (if applicable): Not applicable. Main study parameters/endpoints: The main study parameters are CPM and TS values at baseline and at 3 and 6 months after surgery, as well as the absence/presence of allodynia at baseline and at 3 and 6 months after surgery. Nature and extent of the burden and risks associated with participation, benefit and group relatedness: The burden of participation will consist of completing questionnaires at baseline and at three and six months after surgery. In addition, subjects will undergo psychophysical testing at 3 moments, which can lead to redness or a burning sensation of the skin during the first 24 hours after testing. The investigators do not expect any additional risks associated with participation. There is no direct benefit for the subjects.

NCT ID: NCT05615246 Recruiting - Clinical trials for Rheumatoid Arthritis

Exactech Humeral Reconstruction Prosthesis of Shoulder Arthroplasty PMCF (HRP)

HRP
Start date: September 5, 2018
Phase:
Study type: Observational

The objective of this study is to collect and evaluate long-term clinical outcomes data in order to better understand the safety and performance of the Equinoxe Humeral Reconstruction Prosthesis in shoulder arthroplasty over time. This study will follow subjects for a period of up to 10 years post-surgery.

NCT ID: NCT05500066 Enrolling by invitation - Clinical trials for Rheumatoid Arthritis

AEQUALIS™ FLEX REVIVE™ Study (REVIVE)

REVIVE
Start date: January 11, 2023
Phase:
Study type: Observational

This is an international, single arm, multicenter, prospective, non-significant risk, Post-Market Clinical Follow-up (PMCF) study. Data will be collected for the commercially available AEQUALIS FLEX REVIVE shoulder system in both the anatomic and reversed configurations. The purpose of this study is to collect data needed to satisfy the European Union (EU) Medical Device Regulation (MDR) clinical post-market surveillance (PMS) and reporting requirements, and to support future regulatory submissions and peer-reviewed publications on device performance and safety.

NCT ID: NCT05487274 Recruiting - Clinical trials for Osteoarthritis Shoulder

TSA v RSA in Osteoarthritic Shoulders With Greater Than 15 Degrees of Retroversion

SERVASA15
Start date: August 9, 2022
Phase: N/A
Study type: Interventional

This study will compare total shoulder arthroplasty (TSA) with an augmented glenoid component and reverse shoulder arthroplasty (RSA) procedures, in participants with advanced glenohumeral osteoarthritis aged 65 years and older, who also present with greater than 15 degrees of glenoid retroversion, in the context of a prospective, randomized controlled trial to determine the optimal treatment in this patient population.

NCT ID: NCT05067543 Enrolling by invitation - Avascular Necrosis Clinical Trials

Perform Humeral System Study

PHS
Start date: September 12, 2021
Phase:
Study type: Observational

The purpose of this study is to collect data needed to satisfy the European Union (EU) Medical Device Regulation (MDR) clinical post-market surveillance (PMS) and reporting requirements, and to support future regulatory submissions and peer-reviewed publications on device performance and safety.