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Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection — BMAC  

Osteoarthritis of the Knee Clinical Trial

Official title:
Bone Marrow Aspirate Concentrate vs Corticosteroid Injection for Symptomatic Osteoarthritis (OA) of the Knee: A Randomized Controlled Trial

Clinical Trial Summary

Prospective single-masked (study participant will be masked), randomized controlled trial to examine the influence of BMAC on patient-reported outcomes (PROs) in patients with primary knee osteoarthritis.

Clinical Trial Description

The purpose of this study is to examine the influence of BMAC on patient-reported outcomes (PROs) in patients with primary knee osteoarthritis and compare that to patients receiving corticosteroid injections with six-month follow-up. All patients who sign the consent form will be enrolled in the study and randomized to one of the two treatment arms. This study will aim to recruit and enroll a total of 100 patients (50 per group). Treatment arms include BMAC injections (ARM1) and corticosteroid injections (ARM 2). Patients in the corticosteroid injection group (ARM 2) will receive a sham incision. Follow-up will be up to six months (12-months if crossover (ARM 3)). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05985785
Study type Interventional
Source Rush University Medical Center
Contact Carla M. Edwards, PhD
Phone 312-563-5735
Email carla_edwards@rush.edu
Status Recruiting
Phase N/A
Start date July 19, 2022
Completion date March 31, 2026
View Details
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