Osteoarthritis of the Knee Clinical Trial
Official title:
A Randomized, Placebo-controlled, Double-blind Study to Evaluate the Safety and Efficacy of Three Intra-articular Injections of Ampion™ (4 mL) Administered Two Weeks Apart in Adults With Pain Due to Osteoarthritis of the Knee
This study will evaluate the efficacy of three intra-articular injections, given 2 weeks apart, of Ampion™ in Adults with pain due to osteoarthritis of the knee.
A randomized, placebo-controlled, double-blinded study to evaluate the efficacy and safety of repeated intra-articular injections of Ampion™ in adult subjects with advanced osteoarthritis of the knee. The primary study objective was to evaluate the efficacy and safety from Baseline to Week 20 of 3 Ampion™ 4 mL intra-articular (IA) injections vs saline administered 2 weeks apart in improving knee pain in subjects suffering from osteoarthritis (OA) of the knee (OAK). The secondary study objective was to analyze the effect of Ampion 4 mL vs saline on a change in Patient's Global Assessment (PGA) and knee function from Baseline to Week 20. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03277066 -
A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis
|
Phase 2 | |
Recruiting |
NCT03090698 -
Outcomes of Injections in Patients Waiting for Total Knee Replacement
|
Phase 4 | |
Completed |
NCT02556710 -
A Study to Evaluate the Efficacy & Safety of an Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee
|
Phase 3 | |
Withdrawn |
NCT02237846 -
Clinical Study of Umbilical Cord Tissue Mesenchymal Stem Cells (UC-MSC) for Treatment of Osteoarthritis
|
Phase 1/Phase 2 | |
Completed |
NCT02096393 -
Patient Specific Instrumentation in TKR
|
N/A | |
Completed |
NCT01849445 -
Targeted Rehabilitation to Improve Outcome After Knee Replacement- A Physiotherapy Study
|
N/A | |
Completed |
NCT01704157 -
A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cryo-Touch III Device
|
N/A | |
Active, not recruiting |
NCT01374230 -
Long-Term Multicenter Evaluation of the E1® Tibial Bearing
|
N/A | |
Not yet recruiting |
NCT01270412 -
Platelet Rich Plasma (PRP) as a Treatment for Knee Osteoarthritis PRP as a Treatment for Knee Osteoarthritis
|
Phase 2/Phase 3 | |
Completed |
NCT02156440 -
Cross-over Study of the Efficacy and Safety of SierraSil Joint Formula 14 in Osteoarthritis of the Knee
|
Phase 2 | |
Completed |
NCT01410409 -
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
|
N/A | |
Completed |
NCT01207115 -
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee
|
Phase 2 | |
Completed |
NCT01331278 -
A Comparative Study of Knee Systems
|
Phase 4 | |
Completed |
NCT00970008 -
Exploring Massage Benefits for Arthritis of the Knee
|
Phase 2 | |
Completed |
NCT00988091 -
Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee
|
Phase 3 | |
Completed |
NCT00792727 -
HKT-500 in Adult Patients With Osteoarthritis (OA) Knee Pain
|
Phase 3 | |
Completed |
NCT00531427 -
Buprenorphine Transdermal System (BTDS) in Subjects w/Mod-sev Osteoarthritis (OA) Chronic Pain of Knee
|
Phase 3 | |
Completed |
NCT00449696 -
Gel-200 Versus Placebo in Osteoarthritis of the Knee
|
Phase 3 | |
Completed |
NCT04145011 -
Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain
|
N/A | |
Completed |
NCT01430559 -
Effect Of Meloxicam Versus Placebo In Mainland Chinese Patients With Osteoarthritis Of The Knee
|
N/A |