HKT-500 in Adult Patients With Osteoarthritis (OA) Knee Pain

Status Completed

Clinical Trial Summary

Ketoprofen in a topical patch formulation has been demonstrated to be effective for treating mild to moderate pain caused by various musculoskeletal disorders.

Clinical Trial Description

The objective of this study is to demonstrate the short-term multiple dose efficacy and safety of HKT-500 in subjects with pain caused by mild to moderate osteoarthritis of the knee. The goal of the study is to gather additional information about the analgesic efficacy and safety of repeated, 24-hour applications of 2 HKT-500 patches per knee for a total of 28 days in subjects with pain caused by mild to moderate osteoarthritis of the knee. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00792727
Study type	Interventional
Source	Hisamitsu Pharmaceutical Co., Inc.
Contact
Status	Completed
Phase	Phase 3
Start date	September 2007
Completion date	May 2008

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03277066` - A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis	Phase 2
Recruiting	`NCT03090698` - Outcomes of Injections in Patients Waiting for Total Knee Replacement	Phase 4
Completed	`NCT02556710` - A Study to Evaluate the Efficacy & Safety of an Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee	Phase 3
Withdrawn	`NCT02237846` - Clinical Study of Umbilical Cord Tissue Mesenchymal Stem Cells (UC-MSC) for Treatment of Osteoarthritis	Phase 1/Phase 2
Completed	`NCT02242435` - A Multiple Injection Study Evaluating Safety and Efficacy of Ampion in Osteoarthritis	Phase 3
Completed	`NCT01849445` - Targeted Rehabilitation to Improve Outcome After Knee Replacement- A Physiotherapy Study	N/A
Completed	`NCT02096393` - Patient Specific Instrumentation in TKR	N/A
Completed	`NCT01704157` - A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cryo-Touch III Device	N/A
Active, not recruiting	`NCT01374230` - Long-Term Multicenter Evaluation of the E1® Tibial Bearing	N/A
Completed	`NCT01410409` - Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement	N/A
Completed	`NCT02156440` - Cross-over Study of the Efficacy and Safety of SierraSil Joint Formula 14 in Osteoarthritis of the Knee	Phase 2
Not yet recruiting	`NCT01270412` - Platelet Rich Plasma (PRP) as a Treatment for Knee Osteoarthritis PRP as a Treatment for Knee Osteoarthritis	Phase 2/Phase 3
Completed	`NCT01207115` - A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee	Phase 2
Completed	`NCT01331278` - A Comparative Study of Knee Systems	Phase 4
Completed	`NCT00988091` - Investigation of 1.2% Sodium Hyaluronate for Treatment of Painful Chronic Osteoarthritis of the Knee	Phase 3
Completed	`NCT00970008` - Exploring Massage Benefits for Arthritis of the Knee	Phase 2
Completed	`NCT00531427` - Buprenorphine Transdermal System (BTDS) in Subjects w/Mod-sev Osteoarthritis (OA) Chronic Pain of Knee	Phase 3
Completed	`NCT00449696` - Gel-200 Versus Placebo in Osteoarthritis of the Knee	Phase 3
Completed	`NCT04145011` - Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain	N/A
Completed	`NCT01430559` - Effect Of Meloxicam Versus Placebo In Mainland Chinese Patients With Osteoarthritis Of The Knee	N/A