Osteoarthritis of the Knee Clinical Trial
Official title:
Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty
Total knee arthroplasty (TKA) is associated with moderate to severe postoperative pain,
causing patient discomfort, mobilisation and hospital discharge.
The aim of this study is to:
1. Compare analgetic efficacy of to types of local infiltration analgesia in total knee
arthroplasty.
2. Compare analgetic efficacy of local infiltration analgesia with continuous epidural
analgesia.
Total knee arthroplasty (TKA) is increasingly common in the treatment of knee
osteoarthritis. TKA is associated with moderate to severe postoperative pain, causing
patient discomfort, mobilisation and hospital discharge.
Continuous epidural analgesia is often used for controlling pain after TKA. Recent studies
describe a new method for pain control after total knee arthroplasty which consists of local
infiltration with local anesthetics and adrenaline. This infiltrations can be combined with
ketorolac and/or morphine. The aim of this study is to:
1. Compare analgetic efficacy of to types of local infiltration analgesia in total knee
arthroplasty.
2. Compare analgetic efficacy of local infiltration analgesia with continuous epidural
analgesia.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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