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Osteoarthritis of the Knee clinical trials

View clinical trials related to Osteoarthritis of the Knee.

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NCT ID: NCT03005873 Completed - Clinical trials for Osteoarthritis of the Knee

Phase IIa, Randomized, Double Blinded, Placebo Controlled, Dose Finding Study for TLC599 in OA Patients

Start date: March 16, 2017
Phase: Phase 2
Study type: Interventional

This trial is a Phase IIa, Randomized, Double blinded, Placebo controlled, Dose finding Study to investigate the safety and efficacy of TLC599 in subjects with osteoarthritis of the knee.

NCT ID: NCT02934672 Completed - Clinical trials for Osteoarthritis of the Knee

KineSpring® System Patient Preference Study

Start date: June 2016
Phase:
Study type: Observational

The primary objectives of the survey are to obtain patient preference information that can be useful during the benefit-risk assessment of the KineSpring System.

NCT ID: NCT02803307 Completed - Clinical trials for Osteoarthritis of the Knee

Single-Dose Administration Trial of TLC599 in Osteoarthritis of the Knee

Start date: June 2015
Phase: Phase 1/Phase 2
Study type: Interventional

This trial is a multi-site, randomized, open-label, parallel, and single-dose administration study to investigate the safety and efficacy of TLC599 in subjects with osteoarthritis of the knee.

NCT ID: NCT02768155 Completed - Clinical trials for Osteoarthritis of the Knee

Evaluation of Amniotic Fluid Product in Knee Osteoarthritis

Start date: April 2016
Phase: N/A
Study type: Interventional

A study evaluating Amniotic Fluid compared to a Saline Placebo Injection in the treatment of subjects with osteoarthritic (OA) knee pain

NCT ID: NCT02762370 Completed - Clinical trials for Type 2 Diabetes Mellitus

Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of the Knee and Type 2 Diabetes

Start date: April 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study was to compare the effects of FX006 and Triamcinolone Acetonide Injectable Suspension, United States Pharmacopeia (USP) (referred to as TCA IR in the protocol) on blood glucose (BG) in patients with osteoarthritis (OA) of the knee and Type 2 diabetes mellitus (DM).

NCT ID: NCT02712957 Completed - Pain Clinical Trials

A Proof-of-Concept Study Assessing NEO6860 in Osteoarthritis Pain

Start date: March 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess NEO6860, a modality selective TRPV1 antagonist, in patients with pain associated with osteoarthritis of the knee.

NCT ID: NCT02637323 Completed - Clinical trials for Osteoarthritis of the Knee

Study to Characterize the PK and Local Extent and Duration of Exposure From FX006 in Patients With OA of the Knee

Start date: November 2015
Phase: Phase 2
Study type: Interventional

The objectives of this study were to characterize the local extent and duration of exposure of TA from FX006 and TCA IR, characterize the systemic PK of FX006 and TCA IR, and assess the safety and general tolerability of a single 5 mL IA injection of 32 mg FX006 relative to 40 mg of TCA IR in patients with OA of the knee.

NCT ID: NCT02611466 Completed - Clinical trials for Osteoarthritis of the Knee

A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee

OAK
Start date: February 16, 2016
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the analgesic efficacy of ASP7962 relative to placebo. This study will also evaluate the efficacy of ASP7962 relative to placebo on pain on walking, function and stiffness; the time course of efficacy of ASP7962 relative to placebo; the improvement in overall patient status of ASP7962 relative to placebo as well as the safety and tolerability of ASP7962 relative to placebo.

NCT ID: NCT02604381 Completed - Clinical trials for Osteoarthritis of the Knee

A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee.

13GOHJ
Start date: November 2015
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to assess the effectiveness of alpha-D Glucosamine Sulfate/Standardized Extract of Ginkgo Biloba Leaf versus a comparator product on osteoarthritis pain as assessed by the between group change in WOMAC™ Osteoarthritis Index Pain Subscale using Visual Analogue Scale (VAS) scores in subjects with osteoarthritis of the knee.

NCT ID: NCT02556710 Completed - Clinical trials for Osteoarthritis of the Knee

A Study to Evaluate the Efficacy & Safety of an Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee

Start date: September 2015
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy and safety of an intra-articular injection of AMPION™ in adults with pain due to osteoarthritis of the knee