Clinical Trials Logo

Clinical Trial Summary

Knee osteoarthritis (OA) is a rheumatic disease that causes serious cartilage damage in the knee joint. Moderate physical activity can slow cartilage degeneration in moderate OA stages. Remarkable weakness and atrophy of the quadriceps and hamstrings is a common problem in patients with chronic osteoarthritis, but in arthritis, it may be difficult to achieve strength gains due to the pain caused by heavy load-resistant exercises. Exercising with these high loads may not be possible or may injure painful arthritic knees. For this reason, lately, blood flow restriction exercises have been directed to achieve the same gain by exercising with lower loads by restricting the blood flow with a cuff. We aimed to limit the blood flow in osteoarthritic knees and to provide strength gain and pain reduction provided by conventional exercises given routinely. Our hypothesis in this study is that exercises that blood flow restriction exercises will reduce pain and increase strength as well as conventional exercises.


Clinical Trial Description

Knee osteoarthritis is a rheumatic disease that causes serious cartilage damage in the knee joint. Moderate physical activity can slow cartilage degeneration in moderate OA stages. Remarkable weakness and atrophy of the quadriceps and hamstrings is a common problem in patients with chronic osteoarthritis, but in arthritis, it may be difficult to achieve strength gains due to the pain caused by heavy load-resistant exercises. Exercising with these high loads may not be possible or may injure painful arthritic knees. For this reason, lately, blood flow restricting exercises have been directed to achieve the same gain by exercising with lower loads by restricting the blood flow with a cuff. We aimed to limit the blood flow in osteoarthritic knees and to provide strength gain and pain reduction provided by conventional exercises given routinely. Our hypothesis in this study is that exercises that limit blood flow will reduce pain and increase strength as well as conventional exercises. Forty patients diagnosed with knee osteoarthritis by X-ray will be included in the study. Grade II-III (high rate of exercise therapy) individuals according to the Kellgren Lawrence classification will be included. Patients diagnosed with orthopedics and traumatology will be randomly divided into two groups according to the order of entry through the door. Conventional Exercises that increase muscle strength, flexibility and reduce pain will be included in the first group. In the second group, the same exercises will be used, but during the application, a cuff will be placed on the thigh and the blood flow will be prevented by inflating, therefore, exercises with lower loads will be performed. Exercises will be practiced for 12 weeks and pre-exercise results will be compared within and between groups. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04535596
Study type Interventional
Source Istanbul Medipol University Hospital
Contact
Status Completed
Phase N/A
Start date September 1, 2020
Completion date February 11, 2022

See also
  Status Clinical Trial Phase
Completed NCT05987046 - Contrast Training, Post-activation Countermovement Jump Performance in High Strength Male N/A
Completed NCT04136821 - The Long-term Effects of Oceanix™ on Resistance Training Adaptations N/A
Recruiting NCT05945641 - Effect of Low-load Resistance Training vs. High-intensity Interval Training on Local Muscle Endurance N/A
Completed NCT04069351 - Body Composition Changes During Overfeeding Plus Resistance Training N/A
Not yet recruiting NCT06360536 - Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women N/A
Completed NCT04213586 - Effects of Whey Protein and Collagen Supplementation N/A
Completed NCT05052164 - Improvement Of Physical And Physiological Parameters In Menopausal Or Post-Menopausal Celiac Women N/A
Completed NCT04630951 - Blood Flow Restriction Strength Training in Professional Soccer Players N/A
Not yet recruiting NCT03722277 - Variable Resistance Training in Patients With Osteoarthrosis of the Knee N/A
Completed NCT00991523 - Overnight Post-Exercise Recovery After Protein Ingestion Prior to Sleep N/A
Completed NCT01216722 - Study of Resistance Strengthening Versus Ambulation Post-Liver Transplant N/A
Recruiting NCT06131138 - Aquatic Exercises VS Core Strengthening on Disability, Flexibility and Postural Stability in Weightlifters. N/A
Recruiting NCT06240962 - Mindfulness Practice vs Strength Training on Pain, Kinesiophobia and Function Among Sprinters N/A
Recruiting NCT06131047 - High Intensity Resistance Training With and Without Blood Flow Restriction in ACL Reconstruction N/A
Recruiting NCT06131125 - Plyometric vs Explosive Strength Training on Agility, Power, and Balance in Basketball Players N/A
Completed NCT04315077 - The Short Term Effects of Oceanix Supplementation on Recovery N/A
Completed NCT05597423 - Massage as Recovery Strategy After Resistance Training N/A
Completed NCT02327975 - Prescription of Physical Exercise Through Mobile Application in Elderly N/A
Active, not recruiting NCT06171841 - Effects of Low-Intensity Blood Flow Restriction Training in Normoxia and Hypoxia Conditions N/A
Completed NCT05120440 - The Effect of Breakfast Consumption on Afternoon Resistance Training Performance N/A