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Osteo Arthritis Shoulders clinical trials

View clinical trials related to Osteo Arthritis Shoulders.

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NCT ID: NCT05861960 Recruiting - Clinical trials for Osteoarthritis Shoulder

Endogenous Pain Modulation Study

EPM
Start date: March 4, 2024
Phase:
Study type: Observational

Rationale: Although most patients experience significant pain relief after total shoulder arthroplasty (TSA), pain persists for some patients even after surgery. The endogenous pain system may be involved in persisting postoperative pain in total knee arthroplasty (TKA) and total hip arthroplasty (THA) patients, but this has never been studies for TSA patients. Furthermore, psychological factors and coping strategies may also be of interest but have not yet been extensively studied in TSA patients. Objective: The primary objective is to explore whether central sensitization and/or abnormal CPM responses are present in (a subgroup of) patients who will receive shoulder arthroplasty for osteoarthritis, and whether shoulder arthroplasty produces change in these measures of the endogenous pain modulatory system. The secondary objective, in case patients with altered endogenous pain modulation are found, is to explore if change in pain over time, psychological factors and coping strategies differ between patients with and without altered pain modulation. Study design: An exploratory prospective observational cohort study. Study population: Patients (age 18 years or older) who are scheduled to undergo shoulder arthroplasty for osteoarthritis, at the Reinier Haga Orthopaedic Centre. Intervention (if applicable): Not applicable. Main study parameters/endpoints: The main study parameters are CPM and TS values at baseline and at 3 and 6 months after surgery, as well as the absence/presence of allodynia at baseline and at 3 and 6 months after surgery. Nature and extent of the burden and risks associated with participation, benefit and group relatedness: The burden of participation will consist of completing questionnaires at baseline and at three and six months after surgery. In addition, subjects will undergo psychophysical testing at 3 moments, which can lead to redness or a burning sensation of the skin during the first 24 hours after testing. The investigators do not expect any additional risks associated with participation. There is no direct benefit for the subjects.

NCT ID: NCT05700682 Not yet recruiting - Clinical trials for Osteoarthritis, Knee

Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee

MRI
Start date: March 1, 2023
Phase:
Study type: Observational

In this work the investigators will study the relationship between chronic musculoskeletal pain and abnormal blood flow (neovascularity) around the shoulder, hip and knee. Veterans with as history of chronic shoulder, hip or knee pain and mild/moderate joint degenerative changes will be potential study subjects. Blood flow around joints will be evaluated using perfusion magnetic resonance imaging (MRI). Participants with demonstrably abnormal blood flow around their painful joint will be eligible for enrollment in a pilot study of joint embolization to treat their pain. Participants who choose to not undergo treatment will be re-assessed with MRI after one year to characterize the natural history of joint neovascularity and its relationship to pain.

NCT ID: NCT05641415 Completed - Shoulder Pain Clinical Trials

Finnish Imaging of Shoulder Study

FIMAGE
Start date: February 16, 2023
Phase:
Study type: Observational

In the Finnish Imaging of Shoulder study we will recruit 600 participants from a nationally representative general population sample. Participants aged 40 to 75 years will be invited to a clinical visit that includes assessment of general health, shoulder history and symptoms, and bilateral clinical examination and shoulder imaging (both plain radiography and MRI). We aim to assess the prevalence of abnormal imaging findings in both asymptomatic and symptomatic individuals and explore possible risk factors for abnormal imaging findings and shoulder symptoms.

NCT ID: NCT05603728 Recruiting - Clinical trials for Rheumatoid Arthritis

Exactech Shoulder Post Market Clinical Follow-up Study

Start date: January 2010
Phase:
Study type: Observational

The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performance of the shoulder arthroplasty over time. This study will follow subjects long-term for a minimum of 10-years, without an early-term restriction on the amount of time they will be followed.

NCT ID: NCT05274737 Recruiting - Rotator Cuff Tears Clinical Trials

Comparison Of A Novel Sling With A Traditional Abduction Sling After Shoulder Surgery

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The objective of this study is to determine if the novel shoulder sling has higher patient satisfaction compared to a traditional, abduction sling with at least equivalent postoperative outcomes after arthroscopic rotator cuff repair and total shoulder arthroplasty.

NCT ID: NCT04529798 Recruiting - Clinical trials for Rotator Cuff Tear Arthropathy

Clinical Study Evaluating Outcomes of Reverse Shoulder Arthroplasty With SMR Stemless

SSPR
Start date: November 22, 2016
Phase:
Study type: Observational

The objectives of this study are the assessment of the clinical, radiographical and patient-reported outcomes of SMR Stemless Reverse Shoulder Arthroplasty (LimaCorporate S.p.A.) used as standard of care over a period of at least 2 years of follow-up and the evaluation of the incidence of any complication.

NCT ID: NCT04238143 Recruiting - Osteoarthritis Clinical Trials

Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis

GARM-MSK-ALD
Start date: January 10, 2020
Phase: N/A
Study type: Interventional

Use of Biocellular and cellular approaches to treatment of Osteoarthritis (OA), musculoskeletal aging processes, pain, and degenerative changes are to be studied with minimally invasive protocols, and non-pharmaceutical means to relieve OA and its associated issues. Traditional surgical interventions have not yielded convincing long-term outcomes, including total joint replacement surgeries and medical management of the supportive structures. This study is to use a person's own stem/stromal Cells (autologous) plus HD-PRP (important healing growth factors and signal molecules) in such cases of OA for long-term minimally invasive treatments. Baseline (existing) findings are documented, and thence tracked as to progress deemed to be result of the intervention.

NCT ID: NCT04204265 Completed - Clinical trials for Osteo Arthritis Shoulders

MONOVISC for Shoulder Joint Pain Relief

Start date: December 17, 2019
Phase: N/A
Study type: Interventional

Obtain real world, post market data to confirm the clinical improvement and safety in patients treated with a single injection of MONOVISC for the symptomatic relief of osteoarthritis in the shoulder joint.

NCT ID: NCT03806842 Active, not recruiting - Rotator Cuff Tear Clinical Trials

Easytech Reversed Shoulder System Clinical Study

Start date: November 28, 2018
Phase: N/A
Study type: Interventional

The purpose of the study is to collect data to demonstrate the safety and effectiveness of the Easytech Reversed Shoulder System for the treatment of patients who require a reverse total shoulder arthroplasty.

NCT ID: NCT03782675 Not yet recruiting - Clinical trials for Osteo Arthritis Shoulders

Air Barrier System for the Reduction of Airborne Colony-forming Units During Total Shoulder Arthroplasty

Start date: February 2019
Phase: N/A
Study type: Interventional

The objective of this study is to determine whether the Air Barrier System device reduces airborne colony-forming units (e.g., bacteria) present at a surgery site during total shoulder arthroplasty surgeries.