Effect of Mulligans Mobilization With Movement in Osteoarthritis Knee.

Osteo Arthritis Knee Clinical Trial

Official title:

Effect of Mulligan's Mobilization With Movement Added With Isometric Exercises on Muscle Strength Pain and Disability Associated With Knee Osteoarthritis: A Randomized Controlled Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05577403
• Other study ID #: Shahnaz Hasan
• Status: Completed
• Phase: N/A
• Start date: November 5, 2022
• Est. completion date: November 14, 2023

Study information

• Verified date: November 2023
• Source: Majmaah University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To evaluate the effect of Mulligan's mobilization with movement in osteoarthritis of the knee.

Description:

Patients with knee OA diagnosed at the orthopaedic clinic of Tumair general hospital and referred to the physiotherapy department who attended the rehabilitation centre of Majmaah university will be recruited.

Patients will be excluded if they had knee or hip injury, sensory deficits in the lower extremity, a history of lower-extremity surgery, or a history of a quadriceps or hamstring muscle injury, had low back-related leg pain, or had any contraindication to manual therapy.

The protocol was submitted to and approved by the Majmaah University Research Ethics committee (MUREC Dec.2/ COM-2021/19-3)

Participants will be requested to sign a written informed consent form approved by the institutional ethics committee. A total of 60 participants were randomly assigned to group A (experimental group): Mulligan's mobilization with movement MWM added isometric strength training, and group B (control group): Sham MWM added isometric strength training. Pre and post-test readings were taken at baseline, week 2, and week 4, respectively. The outcome measures for this study will be maximal voluntary isometric contraction of quadriceps strength (measured by ISOMOVE dynamometer), ROM, and Western Ontario and McMaster universities osteoarthritis (WOMAC) index.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: November 14, 2023
• Est. primary completion date: November 10, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 65 Years

Eligibility

Inclusion Criteria:

• Patient with knee OA with radiological evidence of grade 2 or 3 of the Kellgren and Lawrence scale.

• Age between 40-65 years, unilateral or bilateral involvement (in the case of bilateral involvement, the more symptomatic knee was included), and pain in and around the knee.

Exclusion Criteria:

• Patient will be excluded, if they had any deformity of the knee, hip, or back, had any central or peripheral nervous system involvement.

• They had received steroids or intra-articular injection within the previous three months, uncooperative patients.

Related Conditions & MeSH terms

• Osteo Arthritis Knee
• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Behavioral:
• Mulligan's mobilization with movement MWM added isometric strength training
Mulligan's mobilization with movement added isometric exercise: the participants in the experimental group will receive a Mulligan's mobilization with movement added isometric exercise. Treatment will be given for the period of three weeks, for five days a week in both groups. Data will be collected before intervention and after 2nd & 4th week of intervention.

Locations

Country	Name	City	State
Saudi Arabia	Rehabilitation center, Majmaah University	Al Majma'ah	Riyadh

Sponsors (2)

Lead Sponsor	Collaborator
Majmaah University	King Saud University

Country where clinical trial is conducted

Saudi Arabia, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	pain intensity	Visual Analogue scale on 0 to10 cm	6 weeks
Primary	Range of Motion	Standard goniometer.	6 weeks
Primary	Western Ontario and McMaster universities osteoarthritis (WOMAC) index	Western Ontario and McMaster universities osteoarthritis scale	6 weeks