Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty

Osteo Arthritis Knee Clinical Trial

Official title:

Evaluation of the Comparative Analgesic Value of Adductor Canal Block Versus Femoral Block Following Total Knee Arthroplasty

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03395990
• Other study ID #: PRO00067430
• Status: Completed
• Phase: N/A
• Start date: March 27, 2016
• Est. completion date: October 19, 2016

Study information

• Verified date: June 2020
• Source: Duke University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

An observational study of the effect of femoral nerve block in addition to an adductor canal block for pain following total knee arthroplasty.

Description:

Subjects undergoing total knee arthroplasty will receive a preoperative adductor canal block with continuous catheter. Following a standardized general anesthetic for the procedure, subjects will be asked to rate their pain using the NRS-11 pain scale in the recovery room. Once the pain is reported at a 5/10 or above, a femoral nerve block will be performed using either 2% chloroprocaine or saline placebo (randomized). Pain scores are then evaluated over the next 30 minutes by a blinded investigator to determine if the femoral block adds any additional analgesic benefit over an adductor canal block.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: October 19, 2016
• Est. primary completion date: October 19, 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 56 Years to 85 Years

Eligibility

Inclusion Criteria:

• Patients scheduled for elective total knee arthroplasty

• ASA Physical Status I-III

• BMI 18-40 kg/m2

Exclusion Criteria:

• Inability to cooperate with protocol

• Inability to understand or speak English

• Allergy to any local anesthetic

• Chronic opioid consumption/abuse (30 or more morphine mg equivalents/day)

• Contraindication to adductor canal or femoral nerve block

Related Conditions & MeSH terms

• Osteo Arthritis Knee
• Osteoarthritis
• Osteoarthritis, Knee

Intervention

Procedure:
• Active comparator: chloroprocaine
15 ml of 2% chloroprocaine was placed under ultrasound guidance adjacent to the femoral nerve in the operative limb.
• Sham comparator: saline
15 ml of normal saline was placed under ultrasound guidance adjacent to the femoral nerve in the operative limb.

Locations

Country	Name	City	State
United States	Duke University Hospital	Durham	North Carolina

Sponsors (1)

Lead Sponsor	Collaborator
Duke University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain Intensity as Measured by 11-point Verbal Numeric Rating Scale (NRS-11) for Pain.	Pain intensity prior to intervention and at 5 minute intervals after intervention. The 11-point Numeric Rating Scale quantifies a subject's pain experience from 0/10 (no pain) to 10/10 (worst pain imaginable).	Baseline, up to 30 minutes.