Clinical Trials Logo

Clinical Trial Summary

The large body of evidence supports the chemotherapeutic potential of substances found in Olive Oil (OO), acting on different sides, such as inflammation, oxidative damage, and even epigenetic modulation. The consumption of OO should be suggested in a healthy diet instead of other types of oils. It looks worthy, to determine the effect of local application of Olive Oil in decreasing the friction between brackets and wires during orthodontic treatment.


Clinical Trial Description

During the orthodontic treatment, the friction between the bracket and the arch-wire could prevent the action of forces required for a particular tooth movement. Studies demonstrated that approximately 12 to 60% of the force used to move a tooth is dissipated in the form of friction. Consequently, a delay could occur in the biological response to orthodontic movement. The most important factors that may have an impact on friction are; the composition of the bracket, the arch-wire alloy, the cross-sectional size of the arch-wire, the type of ligation system and the surface roughness of the bracket-archwire assembly. In addition to the factors related to the orthodontic appliances, saliva is considered to be a biological variable associated with friction, as it acts as a lubricant during sliding mechanics.This fact should be taken into account in laboratory studies that aim to evaluate the performance of the archwire-bracket combinations. However, in the majority of the research studies, the friction test has been conducted without the use of any lubricant, which does not represent the clinical reality where there is saliva introduced during the movement of the arch-wire on the bracket. To remedy this situation, distilled water has been used as a lubricant. Although in this case the test is conducted in the presence of a lubricant, water does not have the lubricating ability of natural human saliva. It is well known that oil is a well-known lubricant. But how we can use it to decrease friction between brackets and wires? and which type of oil we can use safely in patient mouth? Olive oil (OO) (Olea europaea, Oleaceae) is a fundamental component of the Mediterranean Diet; it is a mix of fatty acids such as oleic and linoleic acid, secoiridoids (oleuropein and oleocanthal), simple phenols (tyrosol and hydroxytyrosol), lignans (pinoresinol), flavonoids (apigenin), hydrocarbons (squalene), triterpenes (maslinic acid), and phytosterols (β-sitosterol). The large body of evidence supports the chemotherapeutic potential of substances found in OO, acting on different sides, such as inflammation, oxidative damage, and even epigenetic modulation. The consumption of OO should be suggested in a healthy diet instead of other types of oils. It looks worthy, to determine the effect of local application of Olive Oil in decreasing the friction between brackets and wires during orthodontic treatment. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05040620
Study type Interventional
Source Minia University
Contact Ahmed Nasef, lecturer
Phone 002-01003383457
Email [email protected]
Status Recruiting
Phase Phase 1
Start date January 1, 2020
Completion date May 1, 2022

See also
  Status Clinical Trial Phase
Not yet recruiting NCT04468295 - Evaluation of the Rate of Maxillary En-masse Retraction Using 0.018-inch Versus 0.022-inch Slot Brackets in Adults N/A
Completed NCT03555747 - Gingival Crevicular Fluid Cytokine Levels in Response to Orthodontic Forces N/A
Recruiting NCT03089996 - Evaluation of Clinical Approaches to Accelerate Orthodontic Tooth Movement N/A
Terminated NCT04386278 - OrthoPulse Gen 2 Initial Device Evaluation and Assessment of Clinical Effectiveness (CA) N/A
Recruiting NCT03299023 - The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)
Completed NCT04044989 - Photobiomodulation and Root Resorption N/A
Completed NCT04070170 - Laser Therapy on Orthodontic Tooth Movement N/A
Not yet recruiting NCT04022252 - Investigation of the Photobiomodulation Applications N/A