Clinical Trials Logo

Oral Soft Tissue Conditions clinical trials

View clinical trials related to Oral Soft Tissue Conditions.

Filter by:

NCT ID: NCT06454084 Active, not recruiting - Vasodilation Clinical Trials

Investigation of Endothelium-dependent Vasodilation in Human Gingiva

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The first aim of this study is to create a cumulative dose-response curve for acetylcholine in men (low serum estrogen levels) to determine the lowest concentration with which we can induce a maximal vasodilation effect on the human gingiva. Furthermore, the second aim of this study is the characterization of the age-dependent effect of sex hormones on gingival blood flow, as well as of the gender differences by applying this concentration to premenopausal men and women with low and high estrogen levels, as well as to postmenopausal subjects.

NCT ID: NCT06238154 Completed - Drug Use Clinical Trials

Flurbiprofen Tablet vs Spray In Oral Soft Tissue Wounds

Start date: October 26, 2023
Phase: Phase 4
Study type: Interventional

The amount of active ingredient in tablet form of flurbiprofen is higher than that in the oral spray form. Therefore, based on the hypothesis that the side effects that may occur depending on the dose can be reduced, this clinical study investigated whether tablet and spray form flurbiprofen would have similar effects on postoperative pain in primarily closed soft tissue wounds in the oral region.

NCT ID: NCT06052501 Not yet recruiting - Prosthesis User Clinical Trials

3D Evaluation of the Lip Support in a Full-arch Implant-supported Rehabilitations

Start date: March 30, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to evaluate the impact of a full arch implant-supported prostheses in the lip support. In a complex rehabilitation cases, the process between the diagnosis and the delivery of a prostheses may lead with many clinical and laboratorial choices which influence the final design of the prosthetic work and consequently the facial profile of the patient. The use of 3D facial scanners and advanced superimposition methodology allows the investigators to objectively measure several relevant parameters such as vertical occlusion of dimension and lip support.

NCT ID: NCT06029322 Recruiting - Clinical trials for Oral Soft Tissue Conditions

Collagen Matrix Versus Collagen Membrane as Socket Seal in ARP

Start date: January 2, 2024
Phase: N/A
Study type: Interventional

Patients in need of extraction of two teeth in combination with alveolar ridge preservation will be invited to participate in intra-subject RCT on ARP. Prior to surgery, a small-field low-dose CBCT is taken. 18 patients will be included, each contributing 1 surgical site to each treatment arm. Since this study is a intra-subject RCT randomization of the surgical site will be performed just after ARP by a coin flip. Randomization is concealed for the evaluating examiner and statistician. After ARP the collagen matrix or collagen membrane is used to seal the coronal aspect of the extraction socket. Soft tissue thickness in centre of the site will be determined using CBCT. Secondary outcomes include: Wound dimensions, socket wound healing score, changes in bone and soft tissue dimensions and changes in buccal soft tissue profile

NCT ID: NCT04918563 Completed - Clinical trials for Oral Soft Tissue Conditions

Endothelium Dependent and Non-dependent Vasodilatation in Human Gingiva

Start date: September 15, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to compare the endothelim-dependent and non-dependent vasodilatation between genders in the human gingiva.

NCT ID: NCT04865952 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

The purpose of the present study is to evaluate the effect of Hyaluronic acid application in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues.

NCT ID: NCT04276129 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part II

Start date: February 20, 2020
Phase: N/A
Study type: Interventional

The purpose of the present study is to evaluate the influence of the post-surgical chlorhexidine indication in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues. The main hypothesis is that the post-surgical use of chlorhexidine affects the gene expression and the celular behavior in the early wound healing process of the soft oral tissues.

NCT ID: NCT04202822 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part I

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

The purpose of the present study is to observe and compare -through a biomolecular analysis- the differences in the gene expression and cellular behavior in the early wound healing process -24 hours after injury- between the following three oral tissues: alveolar mucosa, buccal gingiva and palatal tissue. The main hypothesis is that there is a difference in the gene expression and in the cellular behaviour between the three oral tissues studied and this difference can be observed at 24 hours post-injury.

NCT ID: NCT04131283 Completed - Vasoconstriction Clinical Trials

Evidence of Spreading Vasoconstriction in Human Gingiva

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to observe the mechanism of spreading vasoconstriction in human healthy gingiva. Epinephrine solution is applied on the attached gingiva in group "A" and on the surface of the tooth next to the ginvial sulcus in group "B". The different placement of the solution causes different effect in the microcirculation.

NCT ID: NCT03717389 Not yet recruiting - Clinical trials for Oral Soft Tissue Conditions

The Prevalence of Soft Tissue Calcifications in the Head and Neck Region Using CBCT Among Egyptian Population

Start date: November 2018
Phase:
Study type: Observational

Prevalence of soft tissue calcifications in the head and neck region is not clearly studied in the Egyptian population. Determining the incidence of these calcifications can improve the knowledge of dental practitioners and allow such practitioners to initiate proper diagnostic. And if patients need treatment they can start early by the right therapy to stop the. The aim of this research is to detect and quantify the prevalence of the soft tissue calcifications by cone beam computed tomography (CBCT) images of the head and neck region in the Egyptian population.