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Oral Soft Tissue Conditions clinical trials

View clinical trials related to Oral Soft Tissue Conditions.

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NCT ID: NCT06238154 Completed - Drug Use Clinical Trials

Flurbiprofen Tablet vs Spray In Oral Soft Tissue Wounds

Start date: October 26, 2023
Phase: Phase 4
Study type: Interventional

The amount of active ingredient in tablet form of flurbiprofen is higher than that in the oral spray form. Therefore, based on the hypothesis that the side effects that may occur depending on the dose can be reduced, this clinical study investigated whether tablet and spray form flurbiprofen would have similar effects on postoperative pain in primarily closed soft tissue wounds in the oral region.

NCT ID: NCT04918563 Completed - Clinical trials for Oral Soft Tissue Conditions

Endothelium Dependent and Non-dependent Vasodilatation in Human Gingiva

Start date: September 15, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to compare the endothelim-dependent and non-dependent vasodilatation between genders in the human gingiva.

NCT ID: NCT04865952 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

The purpose of the present study is to evaluate the effect of Hyaluronic acid application in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues.

NCT ID: NCT04276129 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part II

Start date: February 20, 2020
Phase: N/A
Study type: Interventional

The purpose of the present study is to evaluate the influence of the post-surgical chlorhexidine indication in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues. The main hypothesis is that the post-surgical use of chlorhexidine affects the gene expression and the celular behavior in the early wound healing process of the soft oral tissues.

NCT ID: NCT04202822 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part I

Start date: April 1, 2019
Phase: N/A
Study type: Interventional

The purpose of the present study is to observe and compare -through a biomolecular analysis- the differences in the gene expression and cellular behavior in the early wound healing process -24 hours after injury- between the following three oral tissues: alveolar mucosa, buccal gingiva and palatal tissue. The main hypothesis is that there is a difference in the gene expression and in the cellular behaviour between the three oral tissues studied and this difference can be observed at 24 hours post-injury.

NCT ID: NCT04131283 Completed - Vasoconstriction Clinical Trials

Evidence of Spreading Vasoconstriction in Human Gingiva

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to observe the mechanism of spreading vasoconstriction in human healthy gingiva. Epinephrine solution is applied on the attached gingiva in group "A" and on the surface of the tooth next to the ginvial sulcus in group "B". The different placement of the solution causes different effect in the microcirculation.

NCT ID: NCT03605095 Completed - Vasodilation Clinical Trials

Evidence of Spreading Vasodilation in Human Gingiva

Start date: July 25, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to observe the mechanism of spreading vasodilatation on human healthy gingiva. Nitric-oxide donor solutions in lower and higher concentration are used to trigger the vasoactivity.

NCT ID: NCT03335683 Completed - Clinical trials for Oral Soft Tissue Conditions

Phytotherapy Agent in Third Molar Surgery

Start date: January 7, 2016
Phase: Phase 4
Study type: Interventional

The aim of the present study was to evaluate the effect of a phytotherapy agent on clinical and inflammatory parameters, for the postoperative therapy of the impacted third molar surgery. The null hypothesis to invalidate was that, after the last follow-up, there were no variations between the phytotherapy agent and the placebo.

NCT ID: NCT02513368 Completed - Clinical trials for Oral Soft Tissue Conditions

Peri Implant Soft Tissue Healing in Single Implant Restoration Using Two Different Techniques

Start date: January 2011
Phase: Phase 2
Study type: Interventional

The aim of the present study was to propose the employment of Bio-Oss® and Bio-Gide® at implant site in order to evaluate if the increased bucco-lingual bone thickness could enhance the stability of peri implant soft tissue, when compared to the grafting technique ( bilaminar technique), performed in association with implant placement .