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NCT01039272 Clinical Trial

Epstein-Barr Detection in Oral Cancer

Oral Cancer Clinical Trial

Official title:
Epstein-Barr Detection in Squamous Cell Carcinoma and Healthy Oral Mucosa

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01039272
Other study ID # upeclin/FOA-Unesp-03
Secondary ID
Status Completed
Phase N/A
First received December 22, 2009
Last updated June 24, 2015
Start date March 2008
Est. completion date June 2015

Study information
Verified date June 2015
Source UPECLIN HC FM Botucatu Unesp
Contact n/a
Is FDA regulated No
Health authority Brazil: National Committee of Ethics in Research
Study type Observational

Clinical Trial Summary

The aim of this study is to analyze oral squamous cell carcinoma and healthy oral mucosa for the possible presence of Epstein-Barr virus (EBV).

Description:

Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction.

Recruitment information / eligibility
Status Completed
Enrollment 60
Est. completion date June 2015
Est. primary completion date April 2008
Accepts healthy volunteers No
Gender Both
Age group 40 Years and older
Eligibility Inclusion Criteria:

- patients of Oral Cancer Centre - UNESP/Araçatuba - SP

- with oral squamous cell carcinoma

Exclusion Criteria:

- without oral squamous cell carcinoma

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
Brazil Department of Pathology and Propaedeutics, Sao Paulo State University, Unesp, Araçatuba/SP Araçatuba São Paulo

Sponsors (1)
Lead Sponsor Collaborator
UPECLIN HC FM Botucatu Unesp

Country where clinical trial is conducted

Brazil, 

Outcome
Type Measure Description Time frame Safety issue
Primary presence of EBV Epstein-Barr virus has been implicated in a range of malignant neoplasms, including in some studies, in the aetiology of oral squamous cell carcinoma but the influence of EBV in oral cancer remains unclear. This study will examine the prevalence of EBV infection in oral cancer by means of nested polymerase chain reaction. 1 hour No
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