Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03362255
Other study ID # 2017-08-017
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date November 13, 2017
Est. completion date May 5, 2018

Study information

Verified date July 2018
Source Keimyung University Dongsan Medical Center
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

It is reported that optic nerve sheath diameter increases when higher volume of medication is injected during epidural anesthesia.

This study is designed to compare the optic nerve sheath diameter using 10cc of nomal saline of different speed (3cc/sec vs. 1cc/sec).


Description:

It is known that insufficient intraoperative or postoperative management can lengthen the hospital stay with unwanted complications. Therefore, active and proper management using continuous thoracic epidural catheterization is suggested good option to prevent such potential complication.

According to previous study, injection of different volume of local anesthetics (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia, high volume of local anesthetics resulted in significant increase of intracranial pressure (ICP). Increase of ICP can reduce regional cerebral flow and oxygen saturation causing the safety of patients. In addition, increase of ICP can result in headache, syncope, and transient loss of visual acuity.

Although it is very invasive method, ICP can be measured directly at the brain parenchyme. Among methods to measure the ICP indirectly, measurement of optic nerve sheath diameter using ultrasound is known to reflect the degree of ICP. It is reported that optic nerve sheath diameter increases when higher volume of medication is injected during epidural anesthesia.

This study is designed to compare the optic nerve sheath diameter using 10cc of nomal saline of different speed (3cc/sec vs. 1cc/sec).


Recruitment information / eligibility

Status Completed
Enrollment 40
Est. completion date May 5, 2018
Est. primary completion date May 5, 2018
Accepts healthy volunteers No
Gender All
Age group 20 Years to 80 Years
Eligibility Inclusion Criteria:

- lung cancer

- liver cancer

- stomach cancer

- pancreas cancer

Exclusion Criteria:

- coagulopathy

- infection

- previous spine fusion at thoracic level

- previous brain surgery

Study Design


Related Conditions & MeSH terms


Intervention

Other:
thoracic epidural catheterization
thoracic epidural catheterization with different speed of injection

Locations

Country Name City State
Korea, Republic of Ji Hee Hong Daegu

Sponsors (1)

Lead Sponsor Collaborator
Keimyung University Dongsan Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type Measure Description Time frame Safety issue
Primary optic nerve sheath diameter change among 4 time period optic nerve sheath diameter change among 4 time period using ultrasound Baseline, 1 minutes, 10 minutes, 30 minutes after the completion of the intervention
See also
  Status Clinical Trial Phase
Completed NCT06367868 - Optic Nerve Sheath Diameter: A Non-Invasive Indicator of Intracranial Pressure in the Intensive Care Unit Monitoring N/A
Recruiting NCT02697825 - Intraocular Pressure Versus Optic Nerve Sheath Diameter N/A
Not yet recruiting NCT05485363 - Non-invasive Assessment of Intracranial Pressure Using Ocular Sonography in Patients Undergoing Laparoscopic Sleeve Gastrectomy N/A
Not yet recruiting NCT04092036 - Optic Nerve Sheath Diameter in Prediction of Fluid Responsiveness
Not yet recruiting NCT03691025 - Association of the Optic Nerve Sheath Diameter With Eyeball Transverse Diameter in Robot-assisted Prostatectomy
Completed NCT04412109 - Optic Nerve Sheath Diameter Difference Between Different Injection Volume N/A
Completed NCT04826042 - Effect of Contrast Medium on Optic Nerve Sheath Diameter N/A
Completed NCT03152981 - Analysis of Change of Optic Nerve Sheath Diameter in Robot Assisted Laparoscopic Radical Prostatectomy N/A
Completed NCT03131245 - Optic Nerve Sheath Diameter in Craniosynostosis
Recruiting NCT04910087 - The Effect of Anesthesia Management on Optic Nerve Sheath Diameter in the Ercp Procedures N/A
Recruiting NCT04507620 - Effect of Cervical Immobilization on Optic Nerve Sheath Diameter
Recruiting NCT06187714 - Effect of Caudal Block Injection Rate on Optic Nerve Sheath Diameter in Pediatric Surgeries
Completed NCT04955925 - Effect of Sevoflurane and Propofol on the Optic Nerve Sheath Diameter
Not yet recruiting NCT04427085 - Changes of Optic Nerve Sheath Diameter Between Obese and Non-obese Patients Undergoing Laparoscopic Gynecological Surgery N/A
Completed NCT04765397 - Different Resectoscopes Effects to Optic Nerve Sheath Diameter N/A
Completed NCT05499754 - Effect of Different Supralottic Airway Devicess on Optic Nerve Sheath Diameter
Recruiting NCT06254534 - Lidocaine, Dexmedetomidine, Esmolol and Magnesium Effect on Optic Nerve Sheath Diameter After Laryngoscopy N/A
Completed NCT05690087 - Lidocaine Infusion on Optic Nerve Sheath Diameter in Laparoscopic Hysterectomy in Trendelenburg Position N/A
Completed NCT03634176 - Optic Nerve Sheath Diameter in Retrobulbar Ultrasound as a Surrogate Measure for Intracranial Pressure Before and After Non-invasive Strategies
Recruiting NCT06209034 - Intraoperative Optic Nerve Sheath Diameter Changes After Laparoscopic Surgery N/A