Advanced Characterization of Autosomal Dominant Optic Atrophy

Optic Atrophy, Autosomal Dominant Clinical Trial

Official title: Cross Sectional Study of Autosomal Dominant Opticus Atrophy

Status Enrolling by invitation

Clinical Trial Summary

The purpose of this study is to determine the anatomy of the retina and the optic nerve in patients with autosomal dominant optic atrophy (ADOA). Based on these findings the aim of the study is to determine why patients with the same type of genetic material, i.e. the same mutation, have such large variations of symptoms, spanning from unaffected subjects to blindness. The project requires examination of both healthy and affected family members.

Clinical Trial Description

n/a

Study Design

Observational Model: Family-Based, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Atrophy
• Optic Atrophy
• Optic Atrophy, Autosomal Dominant

• NCT number: NCT01522638
• Study type: Observational
• Source: Glostrup University Hospital, Copenhagen
• Status: Enrolling by invitation
• Phase: N/A
• Start date: December 2011
• Completion date: June 2015