Opioid-Related Disorders Clinical Trial
Official title:
Biobehavioral Studies of Opioid Drug Seeking Behavior: Study 1
Verified date | May 2006 |
Source | National Institute on Drug Abuse (NIDA) |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Observational |
The purpose of this study is to determine whether the opportunity to take free supplemental hydromorphone (HYD) influences drug seeking behavior in heroin dependent individuals.
Status | Completed |
Enrollment | 16 |
Est. completion date | July 2005 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 55 Years |
Eligibility |
Inclusion Criteria: - Current opiate dependence, verified by the structured clinical interview for DSM-IV (SCID) and Addiction Severity Index (ASI) - Positive urine test for opiates - Agreement to use adequate contraception for the duration of the study - Able to read and write English Exclusion Criteria: - DSM-IV diagnosis of a psychiatric illness - History of or current neurological disease, including structural brain abnormalities, seizures, infection, peripheral neuropathy, and head trauma - History of cardiovascular disease, myocardial infarction, chest pain, edema, systolic blood pressure greater than 160 mm Hg or less than 95 mm Hg, or diastolic blood pressure greater than 95 mm Hg - Pulmonary disease, including obstructive pulmonary disease, cor pulmonale, tuberculosis, and asthma - Systemic diseases, such as endocrinopathies, liver or kidney failure, myxedema, hypothyroidism, Addison's disease, or autoimmune disease - Current alcohol or sedative drug dependence - Pregnant or breastfeeding - Currently receiving treatment for opioid dependence - Known phobia of injections |
Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | Wayne State University | Detroit | Michigan |
Lead Sponsor | Collaborator |
---|---|
National Institute on Drug Abuse (NIDA) | Wayne State University |
United States,
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