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NCT00000222 Clinical Trial

Alternate-Day Buprenorphine Administration. Phase II - 4

Opioid-Related Disorders Clinical Trial

Official title:
Alternate-Day Buprenorphine Administration. Phase II

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00000222
Other study ID # NIDA-06969-4
Secondary ID R01-06969-4
Status Completed
Phase Phase 1
First received September 20, 1999
Last updated June 23, 2005
Start date July 1992

Study information
Verified date December 1993
Source National Institute on Drug Abuse (NIDA)
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Interventional

Clinical Trial Summary

The purpose of this study is to determine if two times a subject's daily maintenance dose will hold for 48 hours without changes in agonist and antagonist effects.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 28 Years to 45 Years
Eligibility Please contact site for information.

Study Design

Intervention Model: Crossover Assignment, Primary Purpose: Treatment

Related Conditions & MeSH terms

Intervention

Drug:
• Buprenorphine

Locations
Country Name City State
United States Treatment Research Center Burlington Vermont

Sponsors (2)
Lead Sponsor Collaborator
National Institute on Drug Abuse (NIDA) University of Vermont

Country where clinical trial is conducted

United States, 

References & Publications (1)

Amass, bickel, Crean, Blake, Higgins (in press). Alternate day buprenorphine dosing as efficacious and preferred to daily dosing in opioid dependent humans. Psychopharmacology. Amass, Bickel, Crean, Blake, Higgins. (in press) Alternate day buprenorphine dosing as efficacious and preferred to daily dosing in opioid dependent humans. Psychopharmacology

Outcome
Type Measure Description Time frame Safety issue
Primary Drug use
Primary Opioid withdrawal
Primary Opioid agonist effects
Primary Dose identification
Primary Pupil diameter
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