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Opioid-Related Disorders clinical trials

View clinical trials related to Opioid-Related Disorders.

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NCT ID: NCT00000262 Completed - Clinical trials for Substance-Related Disorders

Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14

Start date: November 1996
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effects of combined sevoflurane and nitrous oxide inhalation on mood, psychomotor performance, and the pain response in humans.

NCT ID: NCT00000261 Completed - Clinical trials for Substance-Related Disorders

Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13

Start date: November 1997
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effects of alcohol history on the subjective and reinforcing effects of sevoflurane and nitrous oxide in healthy volunteers. All subjects underwent psychomotor testing during 4 sessions of placebo, drug/placebo, and choice of intervention.

NCT ID: NCT00000260 Completed - Clinical trials for Substance-Related Disorders

Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12

Start date: June 1997
Phase: N/A
Study type: Interventional

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine the effects of different behavioral contingencies in modulating the reinforcing effects of nitrous oxide in healthy volunteers.

NCT ID: NCT00000259 Completed - Clinical trials for Substance-Related Disorders

Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11

Start date: August 1996
Phase: N/A
Study type: Interventional

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine sevoflurane versus isoflurane inhalation at subanesthetic concentrations on mood, pain, and psychomotor performance.

NCT ID: NCT00000258 Completed - Clinical trials for Substance-Related Disorders

Role of Instructions in Nitrous Oxide Effects and Choice - 10

Start date: April 1996
Phase: N/A
Study type: Interventional

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To evaluate the role of instructions in nitrous oxide subjective effects and choice.

NCT ID: NCT00000257 Completed - Clinical trials for Substance-Related Disorders

Effects of Alcohol History on Effects of Nitrous Oxide - 9

Start date: September 1995
Phase: N/A
Study type: Interventional

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To determine effects of alcohol history on the reinforcing, subjective and psychomotor effects of nitrous oxide in healthy volunteers.

NCT ID: NCT00000256 Completed - Clinical trials for Substance-Related Disorders

Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8

Start date: August 1995
Phase: N/A
Study type: Interventional

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine reinforcing effects of brief exposures to nitrous oxide in healthy volunteers.

NCT ID: NCT00000255 Completed - Clinical trials for Substance-Related Disorders

Differential Acute Tolerance Development to Effects of Nitrous Oxide - 7

Start date: April 1995
Phase: Phase 2
Study type: Interventional

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To examine differential acute tolerance development to effects of nitrous oxide in humans.

NCT ID: NCT00000254 Completed - Clinical trials for Substance-Related Disorders

Isoflurane at Subanesthetic Concentrations - 6

Start date: January 1995
Phase: Phase 2
Study type: Interventional

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To test the hypothesis that isoflurane at subanesthetic concentrations does not reduce cold-water immersion pain in healthy volunteers.

NCT ID: NCT00000253 Completed - Clinical trials for Substance-Related Disorders

Effects of Nitrous Oxide: A Dose-Response Analysis - 5

Start date: November 1994
Phase: N/A
Study type: Interventional

The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. To examine the subjective, psychomotor, and reinforcing effects of nitrous oxide in healthy volunteers. This is a dose-response analysis.