Clinical Trials Logo
  1. Home
  2. Opioid Consumption
  3. NCT04176419

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

Opioid Consumption Clinical Trial

Official title:
Investigating the Effect of a Perioperative Analgesia Protocol on Postoperative Opioid Usage and Pain Control in Patients Undergoing Major Head and Neck Cancer Surgery Requiring Microvascular Free Flap Reconstruction

Clinical Trial Summary

The purpose of this study is to determine how a non-opioid pain control regimen, administered before and during surgery, will affect postoperative pain control and total opioid consumption in head and neck cancer participants undergoing cancer surgery with free flap reconstruction.

Clinical Trial Description

This study will help the study team determine how the experimental, non-opioid pain control regimen affects opioid-related side effects, participant satisfaction with pain management, PACU length of stay, hospital length of stay, chronic pain level, and chronic pain-related disability in participants, and to determine the safety and tolerability of the non-opioid pain control regimen in head and neck cancer patients undergoing cancer surgery with free flap reconstruction. Ketamine, Lidocaine, Acetaminophen, Gabapentin, and Celecoxib are FDA-approved drugs that have been approved for use individually, and have been used in combination for perioperative pain control. However, the use of these five drugs together in head and neck cancer patients undergoing free flap reconstruction has not been studied, which is why this study is experimental. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04176419
Study type Interventional
Source Case Comprehensive Cancer Center
Contact
Status Active, not recruiting
Phase Phase 3
Start date January 17, 2020
Completion date October 31, 2024
View Details
See also
  Status Clinical Trial Phase
Completed NCT04017442 - Neuraxial Preservative Free Morphine for Normal Spontaneous Vaginal Delivery Phase 4
Completed NCT03341234 - Superficial Serratus Plane Block for Modified Radical Mastectomy and Axillary Lymph Node Disection N/A
Completed NCT01062906 - Intravenous Lidocaine for Laparoscopic Cholecystectomy N/A
Completed NCT04306159 - Application of Rectus Sheath Block based-on Incision in Upper Abdominal Surgery N/A
Completed NCT05238506 - Lidocaine VS Hemodynamic, Metabolic and Hormonal Response Phase 4
Completed NCT06236035 - Intraoperative Analgesia Based on ANI
Completed NCT05618210 - Effect of ESPB and Rhomboid Block on VATS Method
Not yet recruiting NCT04922359 - Effect of Perioperative Lidocaine on Gastrointestinal Function Recovery After Lumbar Spine Surgery in Adults N/A
Completed NCT03620591 - Lidocaine and Analgesia After Laparoscopic Cholecystectomy N/A
Recruiting NCT04319913 - ANI-guided Intraoperative Analgesia in Low-pressure Anesthesia N/A
Completed NCT01568437 - Transversus Abdominis Plane (TAP) Block in Laparoscopic Gastric-bypass Surgery Phase 3
Completed NCT04915521 - Erector Spinalis Plane Block in Bariatric Surgery N/A
Recruiting NCT06264739 - Erector Spinae Block -Dexmedetomidine N/A
Active, not recruiting NCT06225908 - SPSIPB for Breast Cancer Surgery N/A
Active, not recruiting NCT06226675 - 'The Effect of Adding LFCN Block to PENG N/A
Completed NCT04875572 - Associations Between Analgesia Nociception Index and Preoperative Anxiety N/A
Terminated NCT01157546 - TAP Block for Open Radical Prostatectomy. Phase 1
Completed NCT05845788 - Comparison of the Intraoperative and Postoperative Effects of Ultrasound-guided Erector Spina Plane Block and Posterior Quadratus Lumborum Block in Patients Undergoing Lumbar Stabilization Surgery