Trial of Endocrine Against Locoregional Therapy First in Postmenopausal Women With Early Breast Cancer — REAL  

Operable Breast Neoplasms Clinical Trial

Official title: Randomized Trial of Endocrine Therapy Against Locoregional Therapy First. A DBCG Trial in Postmenopausal Patients With Operable Hormone Receptor Positive Tumors Larger Than 2 cm.

Status Terminated

Clinical Trial Summary

The hypothesis to be addressed in this randomized phase III trial is that 4 months of letrozole may be superior to surgery as primary therapy for early stage hormone receptor positive breast cancer in postmenopausal women, provided that these patients will receive definitive and radical surgery and adjuvant therapies as otherwise indicated at the completion of preoperative letrozole.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Breast Neoplasms
• Operable Breast Neoplasms

• NCT number: NCT00908531
• Study type: Interventional
• Source: Danish Breast Cancer Cooperative Group
• Status: Terminated
• Phase: Phase 3
• Start date: May 2009
• Completion date: December 1, 2013