Clinical Trials Logo
  1. Home
  2. Open-Angle Glaucoma
  3. NCT02438319
  4. Details
NCT02438319 Clinical Trial

Automatic vs. Manual Optic Disc Planimetry

Open Angle Glaucoma Clinical Trial

— Planimetry  

Official title:
Automatic vs. Manual Optic Cup and Optic Disc Segmentation in Glaucoma

Clinical Trial Details — Status: Withdrawn

Administrative data
NCT number NCT02438319
Other study ID # Optic Disc Planimetry
Secondary ID
Status Withdrawn
Phase
First received
Last updated
Start date July 1, 2017
Est. completion date March 20, 2020

Study information
Verified date March 2020
Source University of Zurich
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Manually and automatically by mashing learning algorithm optic disc will be evaluated (planimetry).

Description:

Cross-Over non-randomized Case-Series. Arm 1 (Manual segmentation): Manually marking of the boundaries of the optic disc and it's excavation on color photographs of the optic disc. Arm 2 (Automated segmentation): Automatic detection of the boundaries of the optic disc and it's excavation. Calculation of cup size, size of excavation, cup-to-disc ratio, and rim area. Comparison of all parameters of both arms and computing of agreement.

Recruitment information / eligibility
Status Withdrawn
Enrollment 0
Est. completion date March 20, 2020
Est. primary completion date March 20, 2020
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- open-angle glaucoma

Exclusion Criteria:

- no fundus photography of the optic disc performed

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• manual planimetry
Manually marking of the boundaries of the optic disc and it's excavation on color photographs of the optic disc.
• automated planimetry
Automatic detection of the boundaries of the optic disc and it's excavation on color photographs of the optic disc.

Locations
Country Name City State
n/a

Sponsors (2)
Lead Sponsor Collaborator
University of Zurich Swiss Federal Institute of Technology

References & Publications (1)

Jonas JB. [Glaucoma diagnosis of the optic disc using photography and planimetry]. Ophthalmologe. 2003 Jan;100(1):13-20. German. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary agreement measured by kappa statistics agreement measured by kappa statistics Baseline visit in the outpatient department
Secondary Cup size Cup size Baseline visit in the outpatient department
Secondary size of excavation size of excavation Baseline visit in the outpatient department
Secondary vertical cup to disc ratio vertical cup to disc ratio Baseline visit in the outpatient department
Secondary rim area rim area Baseline visit in the outpatient department
See also
  Status Clinical Trial Phase
Completed NCT03284853 - Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension Phase 3
Terminated NCT03611530 - CoQun Study - (COQUN): a Study to Evaluate the Effects of CoQun in Patients Affected by Open-angle Glaucoma N/A
Not yet recruiting NCT06441643 - Next Generation Rocklatan Phase 2
Not yet recruiting NCT02868502 - Different Glaucoma Treatments Effect on Intraocular Pressure Fluctuation With Postural Change in Eyes With Open-angle Glaucoma N/A
Completed NCT02272569 - STARflo European Safety and Efficacy Study N/A
Completed NCT02628223 - 180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma N/A
Completed NCT01936389 - A Prospective Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Patients With Exfoliation Syndrome and Ocular Hypertension or Glaucoma Phase 2
Completed NCT00941525 - Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressure Phase 4
Completed NCT00539526 - Evaluation of Hyperemia With the Use of Ocular Prostaglandin Analogues Phase 4
Completed NCT00121147 - Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan N/A
Active, not recruiting NCT05035394 - Swedish Microinvasive Glaucoma Surgery Study (SMIGS) N/A
Completed NCT03450629 - Evaluation of Safety and Efficacy of PDP-716 Phase 3
Active, not recruiting NCT06061718 - Travoprost Intraocular Implant in Conjunction With Cataract Surgery Phase 3
Recruiting NCT05241938 - PSLT Compared to Prostaglandin Analogue Eye Drops N/A
Completed NCT01342406 - Effects of Selective Laser Trabeculoplasty on Aqueous Humor Dynamics
Completed NCT02250612 - SYL040012, Treatment for Open Angle Glaucoma Phase 2
Completed NCT01937312 - Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin Analogue Phase 4
Completed NCT01937299 - Effect of SIMBRINZA® Suspension as an Added Therapy to TRAVATAN Z® Phase 4
Terminated NCT01983579 - TF (SENSIMED Triggerfish) in Intraocular Anti-VEGF (Vascular Endothelial Growth Factor) Injection Phase 4
Completed NCT01229982 - A Study Evaluating the Latanoprost Punctal Plug Delivery System (L-PPDS) in Subjects With Ocular Hypertension or Open-Angle Glaucoma Phase 2