Automatic vs. Manual Optic Disc Planimetry

Open Angle Glaucoma Clinical Trial

— Planimetry  

Official title:

Automatic vs. Manual Optic Cup and Optic Disc Segmentation in Glaucoma

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT02438319
• Other study ID #: Optic Disc Planimetry
• Status: Withdrawn
• Start date: July 1, 2017
• Est. completion date: March 20, 2020

Study information

• Verified date: March 2020
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Manually and automatically by mashing learning algorithm optic disc will be evaluated (planimetry).

Description:

Cross-Over non-randomized Case-Series. Arm 1 (Manual segmentation): Manually marking of the boundaries of the optic disc and it's excavation on color photographs of the optic disc. Arm 2 (Automated segmentation): Automatic detection of the boundaries of the optic disc and it's excavation. Calculation of cup size, size of excavation, cup-to-disc ratio, and rim area. Comparison of all parameters of both arms and computing of agreement.

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: March 20, 2020
• Est. primary completion date: March 20, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• open-angle glaucoma

Exclusion Criteria:

• no fundus photography of the optic disc performed

Related Conditions & MeSH terms

• Glaucoma
• Glaucoma, Open-Angle
• Open Angle Glaucoma

Intervention

Other:
• manual planimetry
Manually marking of the boundaries of the optic disc and it's excavation on color photographs of the optic disc.
• automated planimetry
Automatic detection of the boundaries of the optic disc and it's excavation on color photographs of the optic disc.

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
University of Zurich	Swiss Federal Institute of Technology

References & Publications (1)

Jonas JB. [Glaucoma diagnosis of the optic disc using photography and planimetry]. Ophthalmologe. 2003 Jan;100(1):13-20. German. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	agreement measured by kappa statistics	agreement measured by kappa statistics	Baseline visit in the outpatient department
Secondary	Cup size	Cup size	Baseline visit in the outpatient department
Secondary	size of excavation	size of excavation	Baseline visit in the outpatient department
Secondary	vertical cup to disc ratio	vertical cup to disc ratio	Baseline visit in the outpatient department
Secondary	rim area	rim area	Baseline visit in the outpatient department