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Open-Angle Glaucoma clinical trials

View clinical trials related to Open-Angle Glaucoma.

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NCT ID: NCT02558400 Completed - Ocular Hypertension Clinical Trials

Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

Start date: September 18, 2015
Phase: Phase 3
Study type: Interventional

To evaluate ocular hypotensive efficacy and safety of PG324 Ophthalmic Solution compared to Netarsudil (AR-13324) Ophthalmic Solution and Latanoprost Ophthalmic Solution. Following completion of the Month 12 study visit procedures, subjects will be offered the opportunity to participate in a 2-month observational (i.e., non-interventional) trial extension.

NCT ID: NCT02558374 Completed - Ocular Hypertension Clinical Trials

Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension

Start date: September 2015
Phase: Phase 3
Study type: Interventional

To evaluate ocular hypotensive efficacy and safety of Netarsudil (AR-13324) Ophthalmic Solution compared to Timolol Maleate Ophthalmic Solution.

NCT ID: NCT02448875 Completed - Open Angle Glaucoma Clinical Trials

Clinical Evaluation of Visco-Assisted CyPass® Micro-Stent Implantation in Patients With Open Angle Glaucoma

ViscoPass
Start date: June 21, 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the safety and effectiveness of the use of visco-assisted CyPass® Micro-Stent implantation for the lowering of intraocular pressure (IOP) in subjects who have open angle glaucoma (OAG).

NCT ID: NCT02434250 Completed - Cataract Clinical Trials

Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy

SLT
Start date: May 2015
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the efficacy of selective laser trabeculoplasty after a prior failed phacoemulsification and Eximer Laser Trabeculectomy.

NCT ID: NCT02419508 Completed - Ocular Hypertension Clinical Trials

SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA)

Start date: August 7, 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the additive intraocular pressure (IOP) lowering effect of brinzolamide 1%/brimonidine 0.2% (dosed twice per day (BID)) when added to a prostaglandin analogue (PGA) in subjects with open-angle glaucoma or ocular hypertension.

NCT ID: NCT02348476 Completed - Ocular Hypertension Clinical Trials

A Study of Simbrinza™ Therapy in Patients With Open-Angle Glaucoma or Ocular Hypertension

Start date: November 2014
Phase: N/A
Study type: Observational

This study is a retrospective chart review to assess the tolerability and efficacy of treatment with Simbrinza™ used for patients with Open-Angle Glaucoma or Ocular Hypertension.

NCT ID: NCT02339584 Completed - Ocular Hypertension Clinical Trials

Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Start date: April 14, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the fixed combination (BID) [Brinzolamide 10 mg/mL / Brimonidine 2 mg/mL eyes drops, suspension] to the unfixed combination (BID) [Brinzolamide 10 mg/mL eye drops, suspension plus Brimonidine 2 mg/mL eyes drops, solution] with respect to intraocular pressure (IOP)-lowering efficacy.

NCT ID: NCT02325518 Completed - Ocular Hypertension Clinical Trials

Comparison of IOP (Intraocular Pressure)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution

Start date: December 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate AZORGA® Ophthalmic Suspension compared to COSOPT® Ophthalmic Solution for IOP-lowering efficacy in subjects with open-angle glaucoma or ocular hypertension.

NCT ID: NCT02278614 Completed - Ocular Hypertension Clinical Trials

Efficacy and Safety Assessment of T2347 Versus Xalacom® in Ocular Hypertensive or Glaucomatous Patients

Start date: December 2014
Phase: Phase 3
Study type: Interventional

The objective of the study is to assess the efficacy and safety of T2347 (Latanoprost 0.005% + Timolol 0.5% unpreserved eye drops) versus Xalacom® in ocular hypertensive or glaucomatous patients initially treated, stabilised by Xalacom® or generics (fixed combination Latanoprost 0.005% + Timolol 0.5% preserved eye drops).

NCT ID: NCT02272569 Completed - Open Angle Glaucoma Clinical Trials

STARflo European Safety and Efficacy Study

Start date: September 2014
Phase: N/A
Study type: Interventional

Prospective, Non-comparative, Multi-center clinical trial to evaluate the safety and efficacy of the STARflo Glaucoma Implant in patients with refractory open angle glaucoma.