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Oocytes clinical trials

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NCT ID: NCT03700255 Recruiting - Infertility Clinical Trials

Efficacy of a Simulator Based (PickUpSimTM) Residents' Training Program for Oocyte Retrievals

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Simulation is an educational approach that has recently found an application in healthcare.acquire. Angers university hospital has decided to acquire, in December 2016, the high-fidelity Oocyte Pick up (OPU) simulator PickUpSimTM, and the investigators have put in place a training novel program containing different simulation based courses. It is essential to analyze its impact on the clinical practice before implementing it on a larger scale. Initial hypothesis was that the residents' lack of specific training and inexperience would result in suboptimal oocyte retrievals, especially for their first cases The investigators will undertake a prospective comparative study at the In Vitro Fertilization (IVF) unit of the Angers University Hospital between May 2019 and April 2022. The investigators will include all voluntary residents in rotation at the IVF unit in that time period. The participants will be divided in two groups: Group A will undergo the PickUpSimTM simulation training program whereas group B will only have the classic training with no simulation. The primary objective is to assess the benefits of an OPU simulation training program using the PickUpSimTM simulator for teaching residents in a university-affiliated IVF center. The main criterion the investigators will use is the "oocyte retrieval rate" (ORR) during the first month following 15 days of simulation training. The ORR is calculated as the number of oocytes retrieved divided by the number of follicles aspirated. Our secondary objectives are: - To assess the residents' satisfaction with the simulation training program. - To evaluate the learning curve of residents during the two weeks of training. - To compare the OPU complication rate between residents with and without previous simulation training. - To analyze the oocyte retrieval rate in the second and third month of REI rotation for residents, and compare it between those with and those without simulation training.

NCT ID: NCT03307720 Not yet recruiting - Infertility, Female Clinical Trials

Agonist Versus Classical HCG Trigger (Poor Responders, Normoresponders and High Responders)

Start date: December 18, 2017
Phase: N/A
Study type: Interventional

Agonist triggering in controlled ovarian stimulation protocols is being used during last years (among high responder patients to avoid OHSS). Indeed, agonist triggering is more physiologic than HCG triggering. Investigators propose to compare the effectiveness of both types of trigger among three different subsets of patients: 1. Poor responders. 2. Normo-responders 3. High responders Comparing both the number and the quality of achieved oocytes.

NCT ID: NCT02809989 Completed - Pregnancy Rate Clinical Trials

A Study to Evaluate the Effect of Ovaleap® on the Pregnancy Rate and Clinical Effects as Well as the User-friendliness of the Ovaleap®-Pen.

Start date: March 31, 2016
Phase:
Study type: Observational

The aim of this non-interventional study is to extend the knowledge on effectiveness of Ovaleap® (number of oocytes and pregnancy rate) during routine IVF- or ICSI-treatment using a Gonadotropin-releasing hormone (GnRH) antagonist protocol in a large number of patients.