Post Operative Pain Clinical Trial
Official title:
The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section. A Prospective, Observational and Non-inferiority Study Against Epidural Analgesia.
It will be a prospective observational cohort study. The investigators will compare post-cesarean section recovery in patients receiving intravenous infusion of tramadol-ondansetron versus epidural catheter with infusion of local anesthetics.
The primary outcome is to assess the non-inferiority in terms of post-cesarean section recovery of the intravenous perfusion of tramadol + ondansetron compared to the perfusion of local anesthetics through an epidural catheter. This will be a prospective observational cohort study, with a total N of 312 patients who underwent a cesarean section. 156 who maintain the epidural catheter as the main measure of analgesia for 24 h, and 156 who receive an infusion of tramadol-ondansetron from the end of the cesarean section and for the following 24 h. The following data will be collected at 24 and 48 hours: need for unscheduled pharmacological reinforcement, adverse effects, QoR (Quality of Recovery) score 15, ObsQor-10 (Obstetric Quality of Recovery) score, and Visual Analogue Pain Scale (VAS) every 4 hours for 48 hours. The incidence of chronic pain 90 days after cesarean section will be assessed using the Numerical Pain Rating Scale (NRS). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05619796 -
Assessment of Clinical & Radiographic Efficiency of Manual & Pediatric Rotary Systems in Primary Root Canal Preparation
|
N/A | |
| Recruiting |
NCT05338671 -
Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
|
Phase 4 | |
| Completed |
NCT05584696 -
Effectiveness of Green Color Exposure on Dental Anxiety
|
N/A | |
| Completed |
NCT05593341 -
Opioid Education in Total Knee Arthroplasty
|
N/A | |
| Not yet recruiting |
NCT05255146 -
Cryoanalgesia and Post-thoracotomy Pain in Minimally Invasive Cardiothoracic Surgery
|
N/A | |
| Not yet recruiting |
NCT06020196 -
The Safety and Efficacy of Surgical Rectus Sheath Block for Postoperative Analgesia After Elective Cesarean Delivery
|
N/A | |
| Completed |
NCT01697748 -
Prospective Study on Cesarean Wound Outcomes
|
N/A | |
| Completed |
NCT01681966 -
A Single-dose Open-Label Study to Assess the Safety and Preliminary Efficacy of PRF 110 in Open Herniorrhaphy Surgery
|
Phase 2 | |
| Completed |
NCT01442818 -
Patient Satisfaction and Pain Control Following Reconstructive Vaginal Surgery
|
N/A | |
| Completed |
NCT00625911 -
Ketamine Improves Post-Thoracotomy Analgesia
|
N/A | |
| Terminated |
NCT05494125 -
Effects of Continuous ESP Catheters on Recovery, Pain and Opioid Consumption After Multilevel Spine Surgery
|
N/A | |
| Recruiting |
NCT04767399 -
Comparison of Postoperative Pain After Instrumentation in Different Visits With Different Single File Systems.
|
N/A | |
| Not yet recruiting |
NCT05863624 -
Open and Endoscopic Technique in Female Inguinal Hernia Repair. FemaleHernia
|
N/A | |
| Completed |
NCT06048744 -
Ultrasound Guided Erector Spinae Plane Block vs External Oblique Intercostal Plane Block for Nephrectomy
|
N/A | |
| Active, not recruiting |
NCT05374499 -
Double-Blinded Randomized Controlled Study Investigating the Efficacy of Exparel (Liposomal Bupivacaine) for Postoperative Pain Relief in Mandibular Third Molar Extractions
|
Phase 4 | |
| Completed |
NCT06065683 -
Acute Postoperative Pain Prevalence and Intensity in the First 72 Hours
|
||
| Completed |
NCT05510947 -
Acute Postoperative Pain and Catastrophizing in Patients Undergoing Unicompartmental Knee Arthroplasty
|
||
| Completed |
NCT05552391 -
Dexametomedine Versus Ketamine as an Adjuvant in Erector Spinae Block for Perioperative Thoracotomy Pain Control
|
Phase 4 | |
| Completed |
NCT06082479 -
The Effect of Intra Oral Cryotherapy in Patients With Symptomatic Apical Periodontitis
|
N/A | |
| Recruiting |
NCT04909060 -
Does the Newborn Infant Parasympathetic Evaluation (NIPE) Index Predict Postsurgical Pain in Children
|