PEWS Implementation in an LMIC Setting

Oncology Clinical Trial

— PEWSPAL  

Official title:

Implementation of Pediatric Early Warning Scores and a Context-adapted Resuscitation Training Course to Improve Outcomes in an LMIC Pediatric Inpatient Oncology Ward

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04180306
• Other study ID #: PEWSpalestine
• Status: Completed
• Phase: N/A
• Start date: September 1, 2019
• Est. completion date: September 30, 2023

Study information

• Verified date: January 2024
• Source: Boston Children's Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The PEWS implementation study will be undertaken with the following objectives: 1. Assess the effectiveness of implementation of PEWS and resuscitation training to identify patients at risk for clinical deterioration and to impact the frequency of clinical interventions made by treating providers on these patients. 2. Assess the effectiveness of implementation of PEWS and resuscitation training to impact time sensitive clinical interventions made on patients at risk for clinical deterioration. 3. Assess the impact of implementation of PEWS and resuscitation training on length of stay for patients admitted to the pediatric oncology ward.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1850
• Est. completion date: September 30, 2023
• Est. primary completion date: October 31, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 0 Years to 12 Years

Eligibility

Inclusion Criteria:

• Patients eligible for the study are defined as pediatric patients (between birth and 12 years of age) admitted and subsequently discharged from the pediatric oncology ward in Beit Jala, Palestine and Gaza City, Palestine between March 2019 to June 2020

Exclusion Criteria:

• Patients will be excluded if they are not admitted to inpatient status. No oncology outpatients such as those in the infusion program will be included.

Related Conditions & MeSH terms

• Neoplasms
• Oncology

Intervention

Other:
• pediatric early warning scoring system and resuscitation curriculum
teaching resuscitation to medical providers and implementing a scoring tool to help identify patients at risk for clinical deterioration in an inpatient setting

Locations

Country	Name	City	State
Palestinian Territory, occupied	Beit Jala Hospital	Bethlehem
Palestinian Territory, occupied	Rantisi Hospital	Gaza City

Sponsors (1)

Lead Sponsor	Collaborator
Boston Children's Hospital

Country where clinical trial is conducted

Palestinian Territory, occupied, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Elevated Pediatric Early Warning Score (PEWS)	frequency of patients whose PEWS score indicates 'risk for clinical deterioration' and receive a clinical intervention. PEWS 3 or greater (Scale is PEWS 0-6) is defined as at risk for clinical deterioration with a higher score concerning for worse clinical outcome.	1 year
Secondary	Time to antibiotics	Time to antibiotics defined as time from documented vital signs/PEWS to time of antibiotic administration measured in minutes	1 year
Secondary	Time to IV fluid bolus	Time to fluids defined as time from documented vital signs/PEWS to time of documented IV fluid bolus measured in minutes	1 year
Secondary	Volume of IV fluids	Volume of fluids received defined as volume given up to 60 minutes after the initiation of the first fluid bolus measured in milliliters	1 year
Secondary	Length of stay	Length of stay for all patients admitted to the inpatient ward	1 year