Spectral Optical Coherence Tomography Findings in Patients With Ocular Toxoplasmosis

Ocular Toxoplasmosis Clinical Trial

Official title:

Spectral Optical Coherence Tomography Findings in Patients With Ocular Toxoplasmosis : a Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04219176
• Other study ID #: U23454
• Status: Completed
• Start date: January 23, 2002
• Est. completion date: January 2, 2018

Study information

• Verified date: January 2020
• Source: Université de Sousse
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Ocular toxoplasmosis is the most common cause of infectious uveitis worldwide. The diagnosis of ocular toxoplasmosis is primarily clinical when it is a typical presentation .With an atypical presentation in the fundus, parasitological diagnosis is a decisive contribution, as well as multimodal imaging. We investigate on vitreal, retinal, and choroidal morphologic changes in active and scarred toxoplasmosis lesions using swept source optical coherence tomography.

Description:

A retrospective analysis of patients diagnosed with ocular toxoplasmosis was conducted. The patients were examined at ophthalmology service of Farhat Hached Hospital in Sousse Tunisia between January 2002 and December 2017. Complete ophthalmologic examination and OCT were done at the initial visit and during follow-up.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 9
• Est. completion date: January 2, 2018
• Est. primary completion date: March 29, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• all patients hospitalized for ocular toxoplasmosis.

Exclusion Criteria:

• patients with non active ocular toxoplasmosis

Related Conditions & MeSH terms

• Ocular Toxoplasmosis
• Toxoplasmosis

Intervention

Diagnostic Test:
• Spectral optical coherence tomography
Swept-source optical coherence tomography (SS-OCT) is the latest milestone in retinal and choroidal imaging. Because its wavelength of 1050 nm, which is superior to the 840 nm of spectral domain optical coherence tomography (SD-OCT), it is able to overcome ocular opacities such as cataracts and vitritis, wich allows retinal and choroidal visualization of eyes whose fundus is not clearly visible. Consequently , SS-OCT allows visualization of the retinal and choroidal vascular networks, even in eyes with medium opacity

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Université de Sousse

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	number of prticipant affected with ocular toxoplasmosis	patient diagnosed having ocular toxoplasmosis	up to one year