A Three Part Study of MGV354 in Ocular Hypertension or Glaucoma

Status Completed

Clinical Trial Summary

The purpose of this study is to determine if the clinical profile of topical-ocular MGV354 merits further development for the indication of lowering intraocular pressure (IOP).

Clinical Trial Description

Part 1 will evaluate the safety and tolerability of single ascending doses of MGV354 compared to placebo in healthy male and female subjects. Part 2 will evaluate the safety and tolerability of MGV354 in a multiple ascending dose design (two highest tolerated doses from Part 1) compared to placebo when administered for 7 days to patients with ocular hypertension or glaucoma. Part 3 will explore the safety, tolerability and efficacy of a single dose level of MGV354 (maximum tolerated dose) compared to placebo when administered for 7 days in patients with ocular hypertension or glaucoma. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02743780
Study type	Interventional
Source	Alcon Research
Contact
Status	Completed
Phase	Phase 1/Phase 2
Start date	March 2, 2016
Completion date	September 20, 2016

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